Fig. 5
From: The Ussing chamber system for measuring intestinal permeability in health and disease
3% Dextran Sodium Sulphate causes intestinal inflammation and increased intestinal permeability. 10-week-old mice were administered 3% DSS within drinking water for up to nine days to induce acute intestinal inflammation. a Percentage body weight and (b) colon length of animals. c Representative haematoxylin and eosin immunohistochemistry staining of colonic tissue. Asterisks and arrows indicate increased immune cell infiltration and disrupted crypt structure respectively. d TER measurements of proximal colon from DSS treated and untreated animals. e 4 kDa FITC-dextran flux across colonic tissue. n = 4 untreated vs 8 treated. Error bars show +/− SEM