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Table 3 Risk factors of mortality from arterial AMI in ICU: univariate and multivariate analysis

From: Prognostic factors of acute mesenteric ischemia in ICU patients

Characteristics OR 95%CI p-value Adj. OR 95%CI p-value
Demographics
 Gender (male) 0.78 0.44–1.39 0.4
 Age (years) 0.98 0.96–1.008 0.18
CT-scan
 Visualization of vessel obstruction 0.57 0.28–1.12 0.1
 Hypo-enhancement of bowel wall 3.34 1.68–6.62 0.001
 Bowel wall thickening 0.6 0.32–1.12 0.11
 Dilated bowel segment 1 0.53–1.9 0.99
 Fat stranding 0.87 0.43–1.78 0.71
 Pneumatosis intestinalis 1.96 1.006–3.8 0.048
 Air in mesenteric vessels 1.62 0.7–3.72 0.25
 Pneumoperitoneum 0.73 0.35–1.54 0.41
PMH and comorbidities
 Arterial hypertension 0.42 0.21–0.83 0.014
 Diabetes 1.74 0.8–3.80 0.16
 Cardiomyopathy 0.7 0.38–1.26 0.23
 PMH of atrial fibrillation 0.68 0.35–1.27 0.23
 Peripheral artery disease 0.74 0.41–1.33 0.32
Laboratory findings
 CRP 1.01 0.99–1.035 0.24
 Serum creatinine 1.25 1.001–1.55 0.049
 LDH > 250 IU/l 2.56 1.38–4.86 0.003
 Leukocytes 1.02 0.98–1.05 0.22
 NLR 1.003 0.99–1.02 0.7
 INR 7.1 2.8–17.6 < 0.001
 Arterial lactate at diagnosis 1.27 1.14–1.41 < 0.001
 Arterial lactate 24 h after diagnosis 2.1 1.56–2.75 < 0.001
 Arterial delta lactate (after-before) 1.31 1.17–1.48 < 0.001 1.24 1.05–1.48 0.012
 Platelets 24 h before diagnosis 1 0.99–1.002 0.99
Comorbidities and ICU management
 Time from ICU admission to diagnosis 1.1 1.02–1.18 0.011
 New onset of atrial fibrillation during ICU stay 1.36 0.57–3.2 0.48
 Maximal dose of vasopressors 1.26 1.17–1.35 < 0.001 1.20 1.08–1.33 < 0.001
 SCVO2 < 70% or need for inotropic agent 5.42 2.6–11.26 < 0.001
 Anticoagulation 0.26 0.13–0.51 < 0.001 0.19 0.043–0.84 0.029
 Mechanical ventilation 24 h before diagnosis 7.45 3.65–15.2 < 0.001
 SOFA score 1.26 1.12–1.4 < 0.001
 APACHE II score 1.11 1.06–1.17 < 0.001
  1. OR odds ratio, 95%CI: 95% confidence interval, Adj. OR adjusted odds ratio, PMH prior medical history, ICU intensive care unit