Table 3 Risk factors of mortality from arterial AMI in ICU: univariate and multivariate analysis
From: Prognostic factors of acute mesenteric ischemia in ICU patients
Characteristics | OR | 95%CI | p-value | Adj. OR | 95%CI | p-value |
|---|---|---|---|---|---|---|
Demographics | ||||||
Gender (male) | 0.78 | 0.44–1.39 | 0.4 | – | – | – |
Age (years) | 0.98 | 0.96–1.008 | 0.18 | – | – | – |
CT-scan | ||||||
Visualization of vessel obstruction | 0.57 | 0.28–1.12 | 0.1 | – | – | – |
Hypo-enhancement of bowel wall | 3.34 | 1.68–6.62 | 0.001 | – | – | – |
Bowel wall thickening | 0.6 | 0.32–1.12 | 0.11 | – | – | – |
Dilated bowel segment | 1 | 0.53–1.9 | 0.99 | – | – | – |
Fat stranding | 0.87 | 0.43–1.78 | 0.71 | – | – | – |
Pneumatosis intestinalis | 1.96 | 1.006–3.8 | 0.048 | – | – | – |
Air in mesenteric vessels | 1.62 | 0.7–3.72 | 0.25 | – | – | – |
Pneumoperitoneum | 0.73 | 0.35–1.54 | 0.41 | – | – | – |
PMH and comorbidities | ||||||
Arterial hypertension | 0.42 | 0.21–0.83 | 0.014 | – | – | – |
Diabetes | 1.74 | 0.8–3.80 | 0.16 | – | – | – |
Cardiomyopathy | 0.7 | 0.38–1.26 | 0.23 | – | – | – |
PMH of atrial fibrillation | 0.68 | 0.35–1.27 | 0.23 | – | – | – |
Peripheral artery disease | 0.74 | 0.41–1.33 | 0.32 | – | – | – |
Laboratory findings | ||||||
CRP | 1.01 | 0.99–1.035 | 0.24 | – | – | – |
Serum creatinine | 1.25 | 1.001–1.55 | 0.049 | – | – | – |
LDH > 250 IU/l | 2.56 | 1.38–4.86 | 0.003 | – | – | – |
Leukocytes | 1.02 | 0.98–1.05 | 0.22 | – | – | – |
NLR | 1.003 | 0.99–1.02 | 0.7 | – | – | – |
INR | 7.1 | 2.8–17.6 | < 0.001 | – | – | – |
Arterial lactate at diagnosis | 1.27 | 1.14–1.41 | < 0.001 | – | – | – |
Arterial lactate 24 h after diagnosis | 2.1 | 1.56–2.75 | < 0.001 | – | – | – |
Arterial delta lactate (after-before) | 1.31 | 1.17–1.48 | < 0.001 | 1.24 | 1.05–1.48 | 0.012 |
Platelets 24 h before diagnosis | 1 | 0.99–1.002 | 0.99 | – | – | – |
Comorbidities and ICU management | ||||||
Time from ICU admission to diagnosis | 1.1 | 1.02–1.18 | 0.011 | – | – | – |
New onset of atrial fibrillation during ICU stay | 1.36 | 0.57–3.2 | 0.48 | – | – | – |
Maximal dose of vasopressors | 1.26 | 1.17–1.35 | < 0.001 | 1.20 | 1.08–1.33 | < 0.001 |
SCVO2 < 70% or need for inotropic agent | 5.42 | 2.6–11.26 | < 0.001 | – | – | – |
Anticoagulation | 0.26 | 0.13–0.51 | < 0.001 | 0.19 | 0.043–0.84 | 0.029 |
Mechanical ventilation 24 h before diagnosis | 7.45 | 3.65–15.2 | < 0.001 | – | – | – |
SOFA score | 1.26 | 1.12–1.4 | < 0.001 | – | – | – |
APACHE II score | 1.11 | 1.06–1.17 | < 0.001 | – | – | – |