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Table 1 Timing of administration of IMP during mobilisation phase

From: Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study

Day 1 2 3 4 5 6 7 8 9 10 11 12
Cyclophosphamide 1 g/m2            
G-CSF (filgrastim) 5 μg/kg         
Mesna (dose as per local practice)            
PB CD34 count        
Stem cell harvest         a a a a a
  1. aStem cell harvest is approximate, the day of this will depend on adequate CD34+ counts, as described above