Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study

Table 1 Timing of administration of IMP during mobilisation phase

Day	1	5	6	7	8	9	10	11	12
Cyclophosphamide 1 g/m²	✓
G-CSF (filgrastim) 5 μg/kg		✓	✓	✓	✓	✓
Mesna (dose as per local practice)	✓
PB CD34 count					✓	✓	✓	✓	✓
Stem cell harvest					✓^a	✓^a	✓^a	✓^a	✓^a

^aStem cell harvest is approximate, the day of this will depend on adequate CD34+ counts, as described above

ISSN: 1471-230X