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Table 7 Annual costs related to moderate and severe IBS-C

From: Economic burden of moderate to severe irritable bowel syndrome with constipation in six European countries

  FRANCE GERMANY ITALY SPAIN SWEDEN UK
MODERATE SEVERE MODERATE SEVERE MODERATE SEVERE MODERATE SEVERE MODERATE SEVERE MODERATE SEVERE
N 17 37 58 44 43 68 47 64 16 20 21 82
Direct cost to HS (€)
 Mean (95% CI) 421.4 (134.9, 947.3) 961.0 (206.7, 2162.6) 314.4 (163.1, 498.6) 2883.3 (1060.1, 5569.8) 507.0 (187.4, 902.9) 1219.9 (576.8, 2143.1) 675.5 (387.1, 1098.1) 1371.8 (858.4, 1954.0) 1291.0 (185.5, 3384.9) 1264.9 (363.9, 2554.8) 1308.4 (594.4, 2123.6) 2325.0 (1604.3, 3119.0)
 Min, Max 19.0, 3956.0 19.0, 16,761.0 0.0, 3747.0 0.0, 47,390.0 0.0, 5316.0 4.0, 25,363.0 0.0, 6601.0 0.0, 9680.0 0.0, 13,937.7 0.0, 11,657.4 45.7, 6984.1 45.7, 16,773.7
 Median 157.0 201.0 46.0 236.5 64.0 160.5 199.0 357.5 156.7 271.4 590.4 898.9
Direct cost to Patient (€)
 Mean (95% CI) 204.8 (105.2, 340.2) 256.8 (157.1, 410.7) 274.7 (158.2, 412.3) 887.3 (417.6, 1498.7) 289.2 (228.9, 348.6) 612.8 (438.1, 851.8) 539.2 (110.0, 1033.3) 596.0 (341.8, 952.6) 351.3 (168.3, 616.6) 343.5 (225.4, 481.8) 325.2 (93.3, 613.4) 396.2 (212.6, 642.0)
 Min, Max 14.0, 1034.0 14.0, 2358.0 0.0, 2400.0 0.0, 11,506.0 17.0, 739.0 37.0, 6179.0 0.0, 8092.0 0.0, 7004.0 0.0, 1716.0 17.4, 883.4 0.0, 2409.8 0.0, 6500.7
 Median 132.0 164.0 71.0 255.0 256.0 372.5 65.0 149.0 177.8 255.2 72.2 52.9
TOTAL DIRECT COST (€)
 Mean (95% CI) 626.2 (316.4, 1124.0) 1217.8 (405.5, 2446.1) 589.2 (384.0, 824.7) 3770.7 (1814.4, 6496.7) 796.3 (439.3, 1227.0) 1832.7 (1115.4, 2727.7) 1214.7 (683.4, 1783.1) 1967.8 (1355.9, 2651.8) 1642.4 (493.7, 3637.4) 1608.4 (663.0, 3153.5) 1633.6 (850.4, 2508.7) 2721.3 (2003.0, 3545.2)
 Min-Max 33.0, 3978.0 33.0, 17,017.0 0.0, 3822.0 0.0, 48,403.0 17.0, 6055.0 44.0, 28,355.0 0.0, 8245.0 41.0, 10,782.0 29.5, 14,100.0 30.1, 12,175.6 57.7, 7221.0 57.7, 16,780.9
 Median 361.0 334.0 190.0 742.5 315.0 610.0 339.0 648.5 492.6 760.2 829.7 1111.1
Indirect cost (€)
 Mean (95% CI) 2514.1 (125.6, 7733.3) 2464.9 (586.7, 5157.7) 1279.6 (377.1, 2499.4) 4384.7 (2088.3, 7495.6) 297.7 (39.7, 629.3) 370.2 (169.7, 597.6) 362.0 (146.6, 689.7) 2117.6 (328.8, 4725.8) 6710.9 (453.4, 15,788.3) 14,878.4 (4884.1, 29,930.1) 1364.7 (608.3, 2286.3) 4845.1 (2869.9, 7296.5)
 Min, Max 0.0, 37,678.0 0.0, 37,753.0 0.0, 23,714.0 0.0, 50,997.0 0.0, 5232.0 0.0, 4154.0 0.0, 5625.0 0.0, 59,630.0 0.0, 50,979.5 0.0, 101,826.8 0.0, 7015.4 0.0, 45,271.7
Median 0.0 0.0 0.0 64.0 0.0 0.0 0.0 0.0 41.3 2696.4 668.6 93.8
  1. Currency conversion performed on 11th Feb 2014 (EUR/SEK = 8.8183; EUR/GBP = 0.8316)
  2. HS Healthcare system
  3. Bold data are summation of Direct costs to HS + Direct costs to patient
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BMC Gastroenterology

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