Table 7 Annual costs related to moderate and severe IBS-C
FRANCE | GERMANY | ITALY | SPAIN | SWEDEN | UK | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MODERATE | SEVERE | MODERATE | SEVERE | MODERATE | SEVERE | MODERATE | SEVERE | MODERATE | SEVERE | MODERATE | SEVERE | |
N | 17 | 37 | 58 | 44 | 43 | 68 | 47 | 64 | 16 | 20 | 21 | 82 |
Direct cost to HS (€) | ||||||||||||
Mean (95% CI) | 421.4 (134.9, 947.3) | 961.0 (206.7, 2162.6) | 314.4 (163.1, 498.6) | 2883.3 (1060.1, 5569.8) | 507.0 (187.4, 902.9) | 1219.9 (576.8, 2143.1) | 675.5 (387.1, 1098.1) | 1371.8 (858.4, 1954.0) | 1291.0 (185.5, 3384.9) | 1264.9 (363.9, 2554.8) | 1308.4 (594.4, 2123.6) | 2325.0 (1604.3, 3119.0) |
Min, Max | 19.0, 3956.0 | 19.0, 16,761.0 | 0.0, 3747.0 | 0.0, 47,390.0 | 0.0, 5316.0 | 4.0, 25,363.0 | 0.0, 6601.0 | 0.0, 9680.0 | 0.0, 13,937.7 | 0.0, 11,657.4 | 45.7, 6984.1 | 45.7, 16,773.7 |
Median | 157.0 | 201.0 | 46.0 | 236.5 | 64.0 | 160.5 | 199.0 | 357.5 | 156.7 | 271.4 | 590.4 | 898.9 |
Direct cost to Patient (€) | ||||||||||||
Mean (95% CI) | 204.8 (105.2, 340.2) | 256.8 (157.1, 410.7) | 274.7 (158.2, 412.3) | 887.3 (417.6, 1498.7) | 289.2 (228.9, 348.6) | 612.8 (438.1, 851.8) | 539.2 (110.0, 1033.3) | 596.0 (341.8, 952.6) | 351.3 (168.3, 616.6) | 343.5 (225.4, 481.8) | 325.2 (93.3, 613.4) | 396.2 (212.6, 642.0) |
Min, Max | 14.0, 1034.0 | 14.0, 2358.0 | 0.0, 2400.0 | 0.0, 11,506.0 | 17.0, 739.0 | 37.0, 6179.0 | 0.0, 8092.0 | 0.0, 7004.0 | 0.0, 1716.0 | 17.4, 883.4 | 0.0, 2409.8 | 0.0, 6500.7 |
Median | 132.0 | 164.0 | 71.0 | 255.0 | 256.0 | 372.5 | 65.0 | 149.0 | 177.8 | 255.2 | 72.2 | 52.9 |
TOTAL DIRECT COST (€) | ||||||||||||
Mean (95% CI) | 626.2 (316.4, 1124.0) | 1217.8 (405.5, 2446.1) | 589.2 (384.0, 824.7) | 3770.7 (1814.4, 6496.7) | 796.3 (439.3, 1227.0) | 1832.7 (1115.4, 2727.7) | 1214.7 (683.4, 1783.1) | 1967.8 (1355.9, 2651.8) | 1642.4 (493.7, 3637.4) | 1608.4 (663.0, 3153.5) | 1633.6 (850.4, 2508.7) | 2721.3 (2003.0, 3545.2) |
Min-Max | 33.0, 3978.0 | 33.0, 17,017.0 | 0.0, 3822.0 | 0.0, 48,403.0 | 17.0, 6055.0 | 44.0, 28,355.0 | 0.0, 8245.0 | 41.0, 10,782.0 | 29.5, 14,100.0 | 30.1, 12,175.6 | 57.7, 7221.0 | 57.7, 16,780.9 |
Median | 361.0 | 334.0 | 190.0 | 742.5 | 315.0 | 610.0 | 339.0 | 648.5 | 492.6 | 760.2 | 829.7 | 1111.1 |
Indirect cost (€) | ||||||||||||
Mean (95% CI) | 2514.1 (125.6, 7733.3) | 2464.9 (586.7, 5157.7) | 1279.6 (377.1, 2499.4) | 4384.7 (2088.3, 7495.6) | 297.7 (39.7, 629.3) | 370.2 (169.7, 597.6) | 362.0 (146.6, 689.7) | 2117.6 (328.8, 4725.8) | 6710.9 (453.4, 15,788.3) | 14,878.4 (4884.1, 29,930.1) | 1364.7 (608.3, 2286.3) | 4845.1 (2869.9, 7296.5) |
Min, Max | 0.0, 37,678.0 | 0.0, 37,753.0 | 0.0, 23,714.0 | 0.0, 50,997.0 | 0.0, 5232.0 | 0.0, 4154.0 | 0.0, 5625.0 | 0.0, 59,630.0 | 0.0, 50,979.5 | 0.0, 101,826.8 | 0.0, 7015.4 | 0.0, 45,271.7 |
Median | 0.0 | 0.0 | 0.0 | 64.0 | 0.0 | 0.0 | 0.0 | 0.0 | 41.3 | 2696.4 | 668.6 | 93.8 |