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Table 6 Multivariate logistic regressions of clinical and health related quality of life variables for abnormal categorical liver function variables

From: The association of liver function and quality of life of patients with liver cancer

  Child’s classes B to C ALBI grades 2 to 3 Presence of ascites MELD grades 2 to 3
OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value
EORTC QLQ-C30 Physical Functioning 0.987 0.974–1.000 0.045 0.973 0.961–0.985 < 0.001
EORTC QLQ-HCC18 Abdominal Swelling 1.012 1.003–1.021 0.011 1.020 1.012–1.028 < 0.001
CUPI 4.239 2.357–7.626 < 0.001 2.580 1.557–4.277 < 0.001 10.538 5.944–18.681 < 0.001
Bilirubin 1.100 1.073–1.126 < 0.001 1.089 1.058–1.121 < 0.001 1.010 1.001–1.019 0.029 1.093 1.072–1.114 < 0.001
ln(AFP) 0.838 0.763–0.920 0.001 0.790 0.721–0.865 < 0.001
Planned treatment modality 2.149 1.162–3.972 0.015
  1. ALBI albumin-bilirubin, CI Confidence intervals, CUPI the Chinese University Prognostic Index, EORTC European Organization for Research and Treatment of Cancer; ln(AFP) natural logarithm of alpha-feto protein level, MELD Model for End-stage Liver Disease, OR Odds ratio