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Table 3 All-cause and cardiovascular mortality among U.S. Elders, NHANES III (1988–1994)

From: Prevalence and long-term outcomes of non-alcoholic fatty liver disease among elderly individuals from the United States

Mortality outcome by age group

No. of subjects

No. of deaths

Cumulative mortality (%)

5-year Mortality aHR (95% CI)

10-year Mortality aHR (95% CI)

Cumulative mortality aHR (95% CI)

All-cause

 Aged 60–74

  No NAFLD

1122

643

54.02

Reference

Reference

Reference

  NAFLD

973

625

66.23*

1.60 (1.24–1.96)†

1.22 (1.01–1.49)†

1.23 (1.07–1.42)†

 Aged 75 +

 

1112

    

  No NAFLD

715

675

92.21

Reference

Reference

Reference

  NAFLD

461

437

94.20

1.11 (0.88–1.40)

1.17 (0.99–1.36)

1.12 (0.97–1.29)

Cardiovascular disease

 Aged 60–74

  No NAFLD

917

201

15.71

Reference

Reference

Reference

  NAFLD

772

188

20.46*

2.12 (1.20–3.75)†

1.06 (0.73–1.52)

1.20 (0.95–1.52)

 Aged 75 +

  No NAFLD

707

260

34.96

Reference

Reference

Reference

  NAFLD

458

175

36.36

1.05 (0.76–1.44)

1.13 (0.89–1.42)

1.07 (0.90–1.26)

  1. NAFLD was defined as a US FLI score of ≥ 30 in the absence of any other cause of chronic liver disease
  2. Multivariate models were adjusted for male, current smoker, hypertension, hyperlipidemia, advance fibrosis (NFS > .676), and history of CVD and cancer. Age, race, diabetes were not considered because of components of US FLI score
  3. *Significantly different from No NAFLD (p < .05)
  4. †p < .05
  5. abbreviation: CI confidence interval, aHR adjusted Hazard Ratios