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Table 3 Multivariate logistic regression analysis of associated factors and reflux esophagitis

From: What is the impact of metabolic syndrome and its components on reflux esophagitis? A cross-sectional study

Variables Model 1 Model 2 Model 3
Adjusted OR α 95% CI p-value Adjusted OR ß 95% CI p-value Adjusted OR γ 95% CI p-value
Age < 65 years   1.000   1.000  
≥65 years 1.649 1.328–2.048 < 0.001** 1.499 1.203–1.868 < 0.001**
Gender Female 1.000   1.000  
Male 1.317 1.136–1.527 < 0.001** 1.345 1.159–1.560 < 0.001**
BMI (mean ± SD)   1.025 1.004–1.047 0.018*  
Uric acid (mean ± SD) 1.090 1.037–1.145 0.001* 1.096 1.044–1.151 < 0.001**
Smoking No 1.000   1.000   1.000  
Yes 1.443 1.207–1.724 < 0.001** 1.272 1.055–1.533 0.012* 1.294 1.072–1.561 0.007*
Alcohol consumption No 1.000   1.000   1.000  
Yes 1.382 1.183–1.615 < 0.001** 1.286 1.092–1.514 0.003* 1.263 1.072–1.488 0.005*
Betel nuts chewing No 1.000  
Yes 1.211 0.816–1.795 0.342  
Hypertension history No 1.000  
Yes 1.201 1.036–1.393 0.015*  
Diabetes history No 1.000  
Yes 1.433 1.182–1.736 < 0.001**  
H. pylori infection No 1.000  
Yes 1.174 0.890–1.550 0.257  
Hiatal hernia No 1.000   1.000   1.000  
Yes 8.230 2.978–22.745 < 0.001** 7.420 2.677–20.567 < 0.001** 7.490 2.699–20.786 < 0.001**
Abdominal obesity No 1.000   1.000  
Yes 1.352 1.186–1.542 < 0.001**   1.173 1.020–1.349 0.026*
Elevated TG No 1.000  
Yes 1.171 1.022–1.343 0.023*  
Elevated BP No 1.000   1.000  
Yes 1.197 1.056–1.356 0.005*   1.163 1.023–1.323 0.021*
Hyperglycemia No 1.000   1.000  
Yes 1.306 1.144–1.492 < 0.001**   1.306 1.142–1.495 < 0.001**
MetS No 1.000   1.000  
Yes 1.411 1.233–1.616 < 0.001** 1.251 1.071–1.462 0.005*  
MetS components 0 1.000  
1 1.175 0.996–1.386 0.056  
2 1.209 1.014–1.441 0.034*
3 1.615 1.325–1.968 < 0.001**
4 1.603 1.259–2.040 < 0.001**
5 1.514 1.072–2.139 0.018*
  1. Adjusted OR are calculated by N (%) for categorical variables and by mean ± SD for continuous variables using multivariate logistic regression analysis. α Each variable was adjusted for age and gender in the model 1; ß All variables in the model 2 were controlled by each other; γ All variables in the model 3 were controlled by each other
  2. * p < 0.05; ** p < 0.001
  3. BMI body mass index, BP blood pressure, CI confidence interval, H. pylori Helicobacter pylori, MetS metabolic syndrome, N number of patients, SD standard deviation, OR odds ratio, TG triglycerides