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Table 4 Distribution of H. pylori cagA and iceA genotypes according to endoscopic findings and histopathological changes

From: Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes and histopathological changes

 

cagA status N(%)

P. value

iceA status N(%)

Total

P. value

positive

negative

mixed

iceA1

iceA2

mixed

negative

Endoscopic findings

 Normal

9 (45.0)

11 (55.0)

0 (0.0)

0.480

4 (20.0)

6 (30.0)

0 (0.0)

10 (50.0)

20 (100.0)

0.026

 Gastritis

44 (48.4)

44 (48.4)

3 (3.3)

42 (46.2)

31 (34.1)

4 (4.4)

14 (15.4)

91 (100.0)

 Gastric ulcer

4 (40.0)

6 (60.0)

0 (0.0)

6 (60.0)

3 (30.0)

1 (10.0)

0 (0.0)

10 (100.0)

 Duodenal ulcer

6 (85.7)

1 (14.3)

0 (0.0)

2 (28.6)

2 (28.6)

0 (0.0)

3 (42.9)

7 (100.0)

Histopathological changes

 Mild chronic gastritis

3 (60.0)

2 (40.0)

0 (0.0)

0.724

2 (40.0)

3 (60.0)

0 (0.0)

0 (0.0)

5 (100.0)

0 .479

 Moderate chronic gastritis

11 (44.0)

14 (56.0)

0 (0.0)

13 (52.0)

6 (24.0)

2 (8.0)

4 (16.0)

25 (100.0)

 Severe gastritis

2 (100.0)

0 (0.0)

0 (0.0)

2 (100.0)

0 (0.0)

0 (0.0)

0 (0.0)

2 (100.0)

 Chromic active gastritis

47 (49.0)

46 (47.9)

3 (3.1)

37 (38.5)

33 (34.4)

3 (3.1)

23 (24.0)

96 (100.0)

 Total

63 (49.2)

62 (48.4)

3 (2.3)

 

54 (42.2)

42 (32.8)

5 (3.9)

27 (21.1)

128 (100.0)

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