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Table 4 Comparison of the incidence of major drug-related adverse events between groups at the final follow-up

From: Capecitabine plus bevacizumab versus capecitabine in maintenance treatment for untreated characterised KRAS exon 2 wild-type metastatic colorectal cancer: a retrospective analysis in Chinese postmenopausal women

Adverse events

CAP-B (n = 130)

CAP (n = 133)

P-value

Haematological and non-haematological events

18(13.8%)

9(6.9%)

0.059a

Peripheral sensory neuropathy

21(16.2%)

15(11.3%)

0.250a

Myocardial ischaemia

11(8.5%)

6(4.5%)

0.193a

4-grade diarrhoea

14(10.8%)

4(3.0%)

0.013*a

  1. *Statistically significant values. aAnalysed using the Chi-square test. CAP-B capecitabine plus bevacizumab, CAP capecitabine