Table 1 Demographics of 32 patients with Crohn’s disease
N = 32 | Patients without clinical recurrences (n = 13) | Patients with clinical recurrences (n = 19) | p-value | |
|---|---|---|---|---|
Male, n (%) | 22 (68.8) | 10 (76.9) | 12 (63.2) | 0.467 |
Age at inclusion, median (range), yrs. | 22.5 (15–49) | 23.0 (15~ 49) | 22.0 (15~ 38) | 0.260 |
Clinical symptoms, n (%) | ||||
diarrhea | 18 (56.3) | 9 (69.2) | 9 (47.4) | 0.289 |
Abdominal pain | 13 (40.6) | 5 (38.5) | 8 (42.1) | 0.837 |
Bloody stool | 8 (25.0) | 2 (15.4) | 6 (31.6) | 0.299 |
Mucoid stool | 2 (6.3) | 0 (0.0) | 2 (10.5) | 0.502 |
fever | 1 (3.1) | 0 (0.0) | 1 (5.3) | 0.594 |
Weight loss | 3 (9.4) | 1 (7.7) | 2 (10.5) | 0.999 |
Disease, phenotype, n (%), Montreal classification | ||||
L1 (isolated ileal type) | 0 (0) | 0 (0) | 0 (0) | 0.473 |
L2 (isolated colonic type) | 12 (37.5) | 6 (46.2) | 6 (31.6) | |
L3 (ileocolic type) | 20 (62.5) | 7 (53.8) | 13 (68.4) | |
B1 (nonstricturing, nonpenetrating) | 4 (12.5) | 1 (7.7) | 3 (15.8) | 0.528 |
B2 (strcituring) | 17 (53.1) | 7 (53.8) | 10 (52.6) | |
B3 (penetrating) | 11 (34.4) | 5 (38.5) | 6 (31.6) | |
P (concomitant perianal disease) | 14 (43.8) | 4 (30.8) | 10 (52.6) | 0.221 |
Laboratory findings, median value (range) | ||||
WBC, median value (range) | 7100 (2700–13,400) | 7100 (5000–12,600) | 6900 (2700–13,400) | 0.929 |
Hb | 12.9 (9.0–16.0) | 13.6 (10.3–16.0) | 12.9 (9.0–16.0) | 0.421 |
Serum albumin | 4.1 (3.0–5.0) | 4.1 (3.4–5.0) | 4.1 (3.0–5.0) | 0.453 |
C-reactive protein | 1.74 (0.68–3.71) | 2.13 (0.05–7.09) | 1.73 (0.03–7.93) | 0.764 |
Medication, n (%) | ||||
5-Aminosalicylic acid | 28 (87.5) | 11 (84.6) | 17 (89.5) | 0.542 |
Corticosteroid | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0.999 |
Azathioprine | 12 (37.5) | 4 (30.8) | 8 (42.1) | 0.393 |
TNF-α antagonists | 2 (6.3) | 0 (0.0) | 2 (10.5) | 0.345 |
CDAI, median (range) | 93.7 (22.8~ 154.9) | 84.9 (22.8~ 154.9) | 95.9 (46.1~ 147.1) | 0.387 |
SES-CD, median (range) | 14.0 (4~ 37.0) | 13.0 (4.0~ 31.0) | 14.0 (4.0~ 37.0) | 0.486 |