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Table 3 Anthropometric and clinical data (GSRS items) of D-IBS patients according to normal D-IBS(−) or altered D-IBS(+) small intestinal permeability

From: Noninvasive biomarkers of gut barrier function identify two subtypes of patients suffering from diarrhoea predominant-IBS: a case-control study

  D-IBS(−) D-IBS(+)  
Anthropometric parameters
 Sex 2/19 (M/F) 4/14 (M/F)  
 Age (yrs.) 39.89 ± 11.25 40.19 ± 13.24 ns
 BMI 24.48 ± 2.69 23.44 ± 3.76 ns
GSRS single items    p
 Nausea/vomiting 2.0 (1–6) 1.0 (1–4) ns
 Abdominal pain (colic pain) 2.0 (1–6) 4.5 (1–7) ns
 Gastric hunger pain 5.0 (1–7) 2.0 (1–6) ns
 Abdominal distension 5.0 (1–7) 5.0 (1–7) ns
 Burping 1.0 (1–7) 3.0 (1–7) ns
 Borborygmi 3.0 (1–7) 2.5 (1–7) ns
 Flatulence 5.0 (1–7) 3.0 (1–6) ns
 Increased passage of stools 1.0 (1–3) 1.0 (1–7) ns
 Bristol score 5.0 (3–6) 4.0 (3–7) ns
 Urgent bowel movement 3.0 (1–7) 3.0 (1–7) ns
 Feeling of incomplete defecation 4.0 (1–7) 3.0 (1–7) ns
GSRS combination scores
 Abdominal pain 13.0 (8–25) 14.0 (6–25) ns
 Indigestion syndrome 19.0 (12–36) 19.5 (7–39) ns
 Diarrhea syndrome 8.0 (3–21) 6.0 (3–13) ns
  1. D-IBS diarrhoea-predominant IBS, D-IBS patients with a lactulose to mannitol ratio lower than 0.035 were considered D-IBS(−); patients with a ratio value equal to or higher than 0.035 as D-IBS(+). Continuous data are expressed as Mean ± SD, and discrete data are expressed as Median and range. Data were analysed by Mann Whitney test