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Table 2 The Pearson correlation coefficients (r) among the inflammatory parameters and the urinary and circulating intestinal permeability biomarkers in the whole population studied (n. 91 cases)

From: Noninvasive biomarkers of gut barrier function identify two subtypes of patients suffering from diarrhoea predominant-IBS: a case-control study

 

%Ma

%La

La/Ma

%Su

Zonulin

IFAB-P

DAO

IL-6

IL-8

LPS

TLR-4

%Ma

1

          

%La

−0.13

1

         

La/Ma

−0.41****

0.93****

1

        

%Su

0.09

0.67****

0.58****

1

       

Zonulin

−0.22*

0.12

0.17

− 0.12

1

      

IFAB-P

−0.26*

0.61****

0.67****

0.47****

0.10

1

     

DAO

0.04

0.23*

0.27**

0.17

0.10

0.24*

1

    

IL-6

0.05

0.32**

0.32**

0.18

0.24*

0.33**

0.23*

1

   

IL-8

−0.36***

0.33**

0.42****

0.16

0.31**

0.45****

0.22*

0.31**

1

  

LPS

0.05

0.15

0.14

0.06

0.15

0.07

−0.02

0.27*

0.18

1

 

TLR-4

0.16

0.14

0.04

0.7

0.14

0.07

−0.15

0.09

0.07

0.26*

1

  1. %La percentage of ingested lactulose recovered in the urine, %Ma percentage of the ingested mannitol recovered in urine, La/Ma lactulose to mannitol ratio, %Su percentage of ingested sucrose recovered in the urine, I-FABP Intestinal fatty acid binding protein, DAO diamine oxidase
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. ****p < 0.0001