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Table 2 The Pearson correlation coefficients (r) among the inflammatory parameters and the urinary and circulating intestinal permeability biomarkers in the whole population studied (n. 91 cases)

From: Noninvasive biomarkers of gut barrier function identify two subtypes of patients suffering from diarrhoea predominant-IBS: a case-control study

  %Ma %La La/Ma %Su Zonulin IFAB-P DAO IL-6 IL-8 LPS TLR-4
%Ma 1           
%La −0.13 1          
La/Ma −0.41**** 0.93**** 1         
%Su 0.09 0.67**** 0.58**** 1        
Zonulin −0.22* 0.12 0.17 − 0.12 1       
IFAB-P −0.26* 0.61**** 0.67**** 0.47**** 0.10 1      
DAO 0.04 0.23* 0.27** 0.17 0.10 0.24* 1     
IL-6 0.05 0.32** 0.32** 0.18 0.24* 0.33** 0.23* 1    
IL-8 −0.36*** 0.33** 0.42**** 0.16 0.31** 0.45**** 0.22* 0.31** 1   
LPS 0.05 0.15 0.14 0.06 0.15 0.07 −0.02 0.27* 0.18 1  
TLR-4 0.16 0.14 0.04 0.7 0.14 0.07 −0.15 0.09 0.07 0.26* 1
  1. %La percentage of ingested lactulose recovered in the urine, %Ma percentage of the ingested mannitol recovered in urine, La/Ma lactulose to mannitol ratio, %Su percentage of ingested sucrose recovered in the urine, I-FABP Intestinal fatty acid binding protein, DAO diamine oxidase
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. ****p < 0.0001