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Table 1 Anthropometric and biochemical parameters of the study subjects

From: Hepatic expression of Yin Yang 1 (YY1) is associated with the non-alcoholic fatty liver disease (NAFLD) progression in patients undergoing bariatric surgery

  Control (n = 12) Steatosis (n = 20) Non-defining NASH (n = 38) NASH (n = 18) P
Age (years) 33.4 ± 12.9 39.1 ± 12.1 34.2 ± 10.4 34.2 ± 13.1 NS
BMI (kg/m2) 38.1 ± 8.5 37.7 ± 5.02 40.4 ± 7.3 39.4 ± 5.9 NS
Glucose (mmol/L) 4.9 (4.6–5.3) 5.5 (4.8–7.3) 5.5 (5.2–6.5) 6.6 (5.7–8.8) <  0.05#, , &,
Insulin (μIU/mL) 15.3 (12.9–23.1) 19.6 (12.9–31.4) 26.5 (19.6–41.5) 33.4 (20.0–50.8) < 0.05#, , §, &
HOMA-IR 3.6 (3.1–4.4) 4.9 (3.9–8.2) 7.3 (5.2–10.6) 11.5 (5.8–16.9) < 0.05*, #, , §, &
C reactive protein (mg/L) 4.95 (2.75–6.85) 5.9 (4.1–7.4) 6.7 (5.5–11.3) 6.8 (5.1–10.3) NS
Triglycerides (mmol/L) 1.59 (0.96–2.45) 1.43 (1.18–2.04) 1.90 (1.23–2.34) 1.95 (1.52–6.29) NS
Total Cholesterol (mmol/L) 4.7 ± 0.9 4.8 ± 0.9 4.8 ± 0.6 5.4 ± 1.0 NS
HDL-C (mmol/L) 1.05 (0.96–1.50) 1.12 (0.99–1.27) 1.01 (0.83–1.10) 0.92 (0.75–1.02) NS
LDL-C (mmol/L) 3.09 (1.83–3.36) 2.94 (2.15–3.12) 2.71 (2.16–3.35) 2.53 (2.29–3.51) NS
ALT (IU/mL) 19.4 (14.0–28.6) 25.2 (21.0–37.5) 35.8 (27.3–60.2) 76.5 (50.3–128.8) < 0.05#, , &,
AST (IU/mL) 19.5 (15.0–25.4) 20.2 (14.7–25.9) 24.1 (18.5–35.2) 50.5 (29.2–90.7) < 0.05, §, &,
GGT (IU/mL) 35.4 (21.6–53.3) 39.5 (20.2–66.5) 43.5 (26.5–64.0) 55.8 (37.5–90.5) NS
  1. Note: BMI body mass index, HOMA-IR homeostasis model assessment for insulin resistance, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, AST aspartate transaminase, and GGT gamma glutamyltranspeptidase. *, P < 0.05 between the control and steatosis groups; #, P < 0.05 between the control and non-defining NASH groups; , P < 0.05 between the control and NASH groups; §, P < 0.05 between the steatosis and non-defining NASH groups; &, P < 0.05 between the steatosis and NASH groups; , P < 0.05 between the non-defining NASH and NASH groups; and NS, none significance