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Table 2 Anthropometry, lab values and concomitant medication at baseline and week 38, median (range)

From: Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease

 

Baseline

Week 38

Weight, kg (z score for age)

Crohn’s disease (CD)

44.4 (1.05)

48 (1.26)

Ulcerative colitis (UC)

34.3 (1.36)

44 (1.86)

Height, cm

CD

164.0 (138–172)

164.2 (140–172)

UC

146 (127–155)

148 (130–155.5)

Haemoglobin, g/dl

CD

8.4 (6.9–13.0)

10.5 (7.8–12.3)

UC

10.4 (8.0–12,3)

12.1 (8.0–14.8)

Haematocrit, %

CD

26.2 (22.9–40.1)

32.7 (25–38.3)

UC

29.6 (25.0–37.0)

35.8 (25–41.1)

Albumin, g/l

CD

29.6 (18.0–37.5)

35.0 (28.1–42.4)

UC

27.9 (25.6–41.0)

40 (36.5–48.0)

C- reactive protein, mg/dl

CD

4.0 (3.0–8.1)

2.6 (1.7–4.56)

UC

1.1 (0.1–3.0)

0.9 (0.1–2.6)

fecal calprotectin, μg/g stool

CD

not applicable (n/a)

n/a

UC

1482 (84–5910)

187 (5–9750)

Concomitant medication

Corticosteroids

  

  CD, n

4/6

4/6

  dosage, milligram per kilogram bodyweight (mg/KG BW)

0.25 (0.1–0.4)

0.23 (0.1–0.4)

  UC, n

4/5

1/5

  dosage, mg/KG BW

1 (0.5–1.5)

0.2

Azathioprine

CD, n

2/6

2/6

UC, n

1/5

1/5

Mesalazine

CD, n

2/6

2/6

UC, n

0/5

1/5