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Table 1 Univariate analysis of potential risk factors for the development of acute cholecystitis after ERCP

From: Risk factors for post-ERCP cholecystitis: a single-center retrospective study

Variable Acute Cholecystitis Statistic P
No (n = 2636) Yes (n = 36)
Age (y), Mean ± SD 62.4 ± 16.28 62.2 ± 12.90 t = 0.097 0.923
Female 1145 (43.4%) 21 (58.3%) x2 = 2.627 0.105
Past history     
 Hypertension 976 (37.0%) 13 (36.1%) x2 = 0.013 0.910
 Hyperlipemia 70 (2.7%) 1 (2.9%) x2 = 0.005 0.942
 Diabetes mellitus 473 (18.0%) 7 (20.0%) x2 = 0.098 0.755
 Acute pancreatitis 459 (17.4%) 16 (44.4%) x2 = 17.754 < 0.001
 Acute cholangitis 532 (20.2%) 6 (16.7%) x2 = 0.273 0.601
 Chronic cholecystitis 1427 (54.1%) 33 (91.7%) x2 = 20.185 < 0.001
Antibiotics before ERCP 948 (36.0%) 11 (30.6%) x2 = 0.451 0.601
Gallbladder opacification 1016 (38.5%) 24 (66.7%) x2 = 11.816 0.001
Diameter of CBD(cm) 1.2 ± 0.48 1.1 ± 0.42 t = 1.237 0.216
Temperature before ERCP (°C) 36.6 ± 0.58 36.8 ± 0.84 t = −1.891 0.059
Bile duct stents    x2 = 15.805 0.001
 No stent 1174 (66.2%) 19 (52.8%)   
 Metallic stent 414 (15.7%) 14 (38.9%)   
 Plastic stent 436 (16.5%) 2 (5.6%)   
 Metallic+plastic stent 42 (1.6%) 1 (2.8%)   
Laboratory index before ERCP (Median,P25,P75)
 ALT 83.0 (37.3, 193.3) 58.7 (37.5, 191.0) Z = −0.027 0.979
 AST 54.9 (27.9, 119.0) 53.5 (28.7, 83.8) Z = −0.143 0.886
 AKP 198.1 (114.9, 359.8) 196.3 (94.2, 321.2) Z = −0.414 0.679
 GGT 292.5 (125.7, 550.2) 246.9 (91.9, 543.8) Z = −0.181 0.856
 TB 34.9 (15.5, 126.8) 23.7 (13.7, 83.3) Z = −0.845 0.391
 DB 21.2 (6.7, 98.8) 12.8 (7.1, 73.4) Z = −0.641 0.522
 WBC 6.1 (4.8, 8.2) 7.9 (5.9, 11.0) Z = −3.610 < 0.001
 Hemoglobin 125.0 (111.0, 136.0) 131.0 (121.0, 138.0) Z = −1.413 0.158
 Platelet count 192.0 (148.0, 245.0) 192.0 (146.0, 276.0) Z = −0.210 0.833
  1. CBD common bile duct, ALT alanine aminotransferase, AST aspartate anminotransferase, AKP alkaline phosphatase, GGT gamma-glutamyltranspeptidase, TB total bilirubin, DB direct bilirubin, WBC white blood cell