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Table 5 The HR of etiology in the studies

From: Transarterial chemoembolization plus sorafenib for the management of unresectable hepatocellular carcinoma: a systematic review and meta-analysis

Authors (year)

Study design

Aetiology

Endpoint

HR

Kudo et al. (2011) [15]

RCT trial

HBV = 20%

TTP

0.81(0.62–1.07)

  

HCV = 60%

  

Bai et al. (2013) [46]

Comparative study

HBV = 87.9%

OS

1.01(0.60–1.71)

  

HCV = 4.9%

  

Muhammad et al. (2013) [47]

Comparative study

ST:HCV = 69%

OS

1.04(0.66–1.63)

  

DT:HCV = 93%

  

Zhao et al. (2013) [41]

Non-comparative study

HBV = 80%

OS

1.372(0.773–2.437)

  

HCV = 5%

  

Hu et al. (2014) [14]

Comparative study

ST:B = 82.9%

TTP

1.01(0.76–1.34)

  

T:B = 79.8%

  

Yao et al. (2016) [12]

Comparative study

ST:HBV = 84%

OS

1.228(0.593–2.540)

  

T:HBV = 83%

TTP

0.878(0.494–1.561)

  1. Abbreviations: HR hazard ratio, OS overall survival, TTP time to progression, RCT randomized controlled trials, ST sorafenib plus TACE, DT DEB –TACE