Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments

Table 4 Pathway analysis of twelve bile acids in liver cirrhosis compared with healthy volunteers

Pathway name	Hit	P	-log(P)	FDR	Impact
Primary bile acid biosynthesis	5	5.72 × 10–10	21.281	1.05 × 10–9	0.10527
Taurine and hypotaurine metabolism	1	1.05 × 10–9	20.677	1.05 × 10–9	0

Hit means the matched number of bile acid in metabolization pathway; The P value is calculated from the enrichment analysis; Impact value is calculate from pathway topography analysis; FDR value is the false discovery rate adjusted P value

ISSN: 1471-230X