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Table 4 Endoscopic findings for diagnosis as GVHD: univariate and multivariate analysis in patients with pathological GVHD positive and negative

From: Villous atrophy in the terminal ileum is a specific endoscopic finding correlated with histological evidence and poor prognosis in acute graft-versus-host disease after allo-hematopoietic stem cell transplantation

Univariate analysis   Multivariate analysis
  Pathological GVHD(+) Pathological GVHD(−) P-value OR 95% CI P-value
n = 20 n = 31
Part Endoscopic findings n (%) n (%)  
Terminal Villous atrophy 14 75 9 29 0.002 4.69 1.07–20.60 0.04
ileum Edema 4 20 6 19.4 > 0.999  
  Erythema 7 35 2 6.5 0.02 4.67 0.74–29.47 0.10
Shallow ulcer 1 5 0 0 0.39  
Deep ulcer 1 5 0 0 0.39
Erosion 6 30 4 12.9 0.16
Tortoise shell-like 0 0 1 3.2 > 0.999
Congestion 0 0 0 0
Right Edema 13 65 18 58.1 0.77
hemi-colon Erythema 9 45 13 41.9 > 0.999
  Shallow ulcer 3 15 1 3.2 0.29
Deep ulcer 1 5 0 0 0.39
Erosion 9 45 4 12.9 0.02 1.78 0.35–9.16 0.49
Tortoise shell-like 0 0 1 3.2 > 0.999  
Congestion 0 0 0 0
Left Edema 11 55 15 48.4 0.78
hemi-colon Erythema 6 30 8 25.8 0.76
  Shallow ulcer 2 10 2 6.5 0.64
Deep ulcer 2 10 0 0 0.15
Erosion 5 25 5 16.1 0.49
Tortoise shell-like 3 15 1 3.2 0.29
Congestion 0 0 0 0
Rectum Edema 6 30 11 35.5 0.77
  Erythema 5 25 5 16.1 0.49
Shallow ulcer 2 10 0 0 0.14
Deep ulcer 0 0 0 0
Erosion 1 5 1 3.2 > 0.999
Tortoise shell-like 1 5 0 0 0.39
Congestion 0 0 0 0
  1. CI confidence interval, OR odds ratio