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Table 4 Endoscopic findings for diagnosis as GVHD: univariate and multivariate analysis in patients with pathological GVHD positive and negative

From: Villous atrophy in the terminal ileum is a specific endoscopic finding correlated with histological evidence and poor prognosis in acute graft-versus-host disease after allo-hematopoietic stem cell transplantation

Univariate analysis

 

Multivariate analysis

 

Pathological GVHD(+)

Pathological GVHD(−)

P-value

OR

95% CI

P-value

n = 20

n = 31

Part

Endoscopic findings

n

(%)

n

(%)

 

Terminal

Villous atrophy

14

75

9

29

0.002

4.69

1.07–20.60

0.04

ileum

Edema

4

20

6

19.4

> 0.999

 
 

Erythema

7

35

2

6.5

0.02

4.67

0.74–29.47

0.10

Shallow ulcer

1

5

0

0

0.39

 

Deep ulcer

1

5

0

0

0.39

Erosion

6

30

4

12.9

0.16

Tortoise shell-like

0

0

1

3.2

> 0.999

Congestion

0

0

0

0

Right

Edema

13

65

18

58.1

0.77

hemi-colon

Erythema

9

45

13

41.9

> 0.999

 

Shallow ulcer

3

15

1

3.2

0.29

Deep ulcer

1

5

0

0

0.39

Erosion

9

45

4

12.9

0.02

1.78

0.35–9.16

0.49

Tortoise shell-like

0

0

1

3.2

> 0.999

 

Congestion

0

0

0

0

Left

Edema

11

55

15

48.4

0.78

hemi-colon

Erythema

6

30

8

25.8

0.76

 

Shallow ulcer

2

10

2

6.5

0.64

Deep ulcer

2

10

0

0

0.15

Erosion

5

25

5

16.1

0.49

Tortoise shell-like

3

15

1

3.2

0.29

Congestion

0

0

0

0

Rectum

Edema

6

30

11

35.5

0.77

 

Erythema

5

25

5

16.1

0.49

Shallow ulcer

2

10

0

0

0.14

Deep ulcer

0

0

0

0

Erosion

1

5

1

3.2

> 0.999

Tortoise shell-like

1

5

0

0

0.39

Congestion

0

0

0

0

  1. CI confidence interval, OR odds ratio