Table 1 Clinical and laboratory data for patients and controls
Control N = 34 | NAFLD N = 22 | NAFLD with DIOS N = 16 | CLD N = 8 | CLD-IO N = 21 | Compound heterozygous HH N = 5 | Homozygous HH N = 12 | |
|---|---|---|---|---|---|---|---|
Gender (F/M) | 19/15 | 8/14 | 5/11 | 4/4 | 6/15 | 1/4 | 2/10 |
Age (y) | 40 ± 10* | 54 ± 16 | 59 ± 10 | 57 ± 8 | 58 ± 8 | 59 ± 9 | 51 ± 6 |
BMI (kg/m2) | 23.3 ± 2.6* | 30.4 ± 4.2# | 28.1 ± 2.4 | 27.3 ± 5.1 | 27.0 ± 4.2 | 29.0 ± 3.5 | 28.2 ± 4.8 |
Hemoglobin (g/L) | 142 ± 11 | 150 ± 15 | 149 ± 17 | 140 ± 10 | 140 ± 17 | 158 ± 15 | 154 ± 12 |
ALT (U/L) | 18 ± 6* | 94 ± 76 | 59 ± 41 | 71 ± 59 | 53 ± 29 | 41 ± 35 | 82 ± 35 |
CRP (mg/L) | 1.1 ± 0.4 | 3.0 ± 2.9 | 1.8 ± 0.9 | 2.8 ± 3.0 | 3.8 ± 5.5 | 3.6 ± 4.0 | 3.3 ± 2.7 |
Serum ferritin (μg/L) | 94 ± 87 | 304 ± 248 | 816 ± 285¤ | 454 ± 688 | 1304 ± 1295¤ | 878 ± 408¤ | 1753 ± 998¤ |
Transferrin saturation (%) | 0.28 ± 0.11 | 0.28 ± 0.09 | 0.39 ± 0.09 | 0.31 ± 0.15 | 0.50 ± 0.21§ | 0.46 ± 0.10§ | 0.76 ± 0.21* |
Hepatic iron score | N.D. | 0.11 ± 0.21 | 2.19 ± 0.95¤ | 0.29 ± 0.27 | 2.98 ± 1.22¤ | 3.38 ± 0.75¤ | 4.35 ± 0.63¤ |