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Table 4 IBS-QoL scores at baseline, during 16 weeks’ treatment and after one month’s follow-up)

From: A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome

 

Probiotic (Bio-Kult®) (n = 181)

Placebo (n = 179)

P-value

Before treatment

22.6 ± 10.5

27.5 ± 13.0

< 0.001

At 1st month

46.5 ± 13.6

44.8 ± 15.8

0.270

At 2nd month

59.0 ± 18.9

48.7 ± 20.3

< 0.001

At 3rd month

66.4 ± 21.6

47.6 ± 22.9

< 0.001

At 4th month

68.3 ± 21.8

48.4 ± 24.5

< 0.001

At 5th month

72.0 ± 16.5

58.5 ± 16.8

< 0.001

  1. The unpaired t-test was used to determine the level of statistical significance
  2. Note: In this scoring system, higher scores indicate better QoL
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BMC Gastroenterology

ISSN: 1471-230X

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