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Table 4 IBS-QoL scores at baseline, during 16 weeks’ treatment and after one month’s follow-up)

From: A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome

  Probiotic (Bio-Kult®) (n = 181) Placebo (n = 179) P-value
Before treatment 22.6 ± 10.5 27.5 ± 13.0 < 0.001
At 1st month 46.5 ± 13.6 44.8 ± 15.8 0.270
At 2nd month 59.0 ± 18.9 48.7 ± 20.3 < 0.001
At 3rd month 66.4 ± 21.6 47.6 ± 22.9 < 0.001
At 4th month 68.3 ± 21.8 48.4 ± 24.5 < 0.001
At 5th month 72.0 ± 16.5 58.5 ± 16.8 < 0.001
  1. The unpaired t-test was used to determine the level of statistical significance
  2. Note: In this scoring system, higher scores indicate better QoL