Pancreatic duct obstruction after pancreaticojejunostomy: implications for early prediction and prevention of long-term pancreatic complications

Table 3 Correlation of postoperative pancreatic duct obstruction with remnant pancreatic morphological changes and clinicopathologic characteristics in patients who underwent pancreatic resection and pancreaticojejunostomy

Variable	Pancreatic duct obstruction after pancreaticojejunostomy		P value
Variable	Present (n = 25)	Absent (n = 53)	P value
Mean age at operation, y	54.6±16.1 (range -)	56.7±16.1 (range 14-79)	0.712
Sex, M:F (%)	17 (68):8 (32)	30 (57):23 (43)	0.458
Pancreatic duct diameter (mm)
Before operation			0.153
Mean ± SD	3.5 ± 2.4	3.0 ± 1.9
Median [range]	2.5 [1.0-10.0]	2.8 [1.0-9.0]
After operation			0.000
Mean ± SD	5.7 ± 2.6	1.8 ± 0.6
Median [range]	[3.3-13.0]	[1.0-3.0]
Pancreatic parenchymal thickness (mm)
Before operation			0.870
Mean ± SD	14.0 ± 4.9	14.3 ± 5.7
Median [range]	18 [10.7-25.0]	17.4 [4.5-30.0]
After operation
Mean ± SD	9.5 ± 4.1	14.1 ± 4.9	0.000
Median [range]	11 [2.5-16.7]	14.7 [3.0-28.3]
Type of operation, n (%)			1.000
Pancreaticoduodenectomy	24	49
Segment resection of pancreas^*	1	4
Pancreatic duct stent retained > 2 years, n (%)	1 (4)	9 (17)	0.155
Adjuvant therapy, n (%)	9 (36)	11 (21)	0.397
I₁₂₅ radioactive seeds implantation, n (%)	2 (8)	1 (2)	0.245
Pancreatic fistula, n (%)	3 (12)	14 (26)	0.240
Malignant tumor, n (%)	13 (52)	30 (57)	0.809
Follow-up period (mo)			0.551
Mean ± SD	39.8 ± 20.4	37.1 ± 22.0

*Segment resection of pancreas: Medial pancreatectomy without duodenectomy and the distal pancreatic stump was covered with invaginated end-to-end panceaticojejunostomy.