Table 1 Comparison of the baseline patients’ characteristics, including demographics and medical histories, between those with perforation and those without perforation by univariate analysis
From: Evaluation of risk factors for perforated peptic ulcer
Case subjects (those with perforation) | Control subjects (those without perforation) | p-value | |
|---|---|---|---|
n = 136 | n = 272 | ||
Patients’ demographics | |||
Agea, year (SD) | 56.2 (16.5) | 56.2 (16.5) | 1.00 |
Malea, n (%) | 116 (85.3) | 232 (85.3) | 1.00 |
Smoking, n (%) | 98 (72.1) | 114 (41.9) | < 0.01 |
Regular alcohol consumption, n (%) | 75 (55.1) | 112 (41.2) | 0.48 |
Medical history | |||
Gastrointestinal history | |||
Peptic ulcer disease, n (%) | 45 (33.1) | 27 (9.9) | < 0.01 |
Gastroesophageal reflux disease, n (%) | 2 (1.5) | 4 (1.5) | 1.00 |
Crohn’s disease, n (%) | 0 (0.0) | 0 (0.0) | N/A |
Ulcerative colitis, n (%) | 1 (0.7) | 1 (0.4) | 1.00 |
H. pylori infection, n (%) | 9 (6.6) | 1 (0.4) | < 0.01 |
Adnominal operation, n (%) | 38 (27.9) | 74 (27.2) | 0.91 |
Prior ESDb, n (%) | 1 (0.7) | 1 (0.4) | 1.00 |
Other history | |||
Hypertension, n (%) | 34 (25.0) | 68 (25.0) | 1.00 |
Diabetes mellitus, n (%) | 19 (14.0) | 32 (11.8) | 0.53 |
Dyslipidemia, n (%) | 12 (8.8) | 42 (15.4) | 0.07 |
Cancer baring, n (%) | 17 (12.5) | 31 (11.4) | 0.75 |
Under chemotherapy, n (%) | 8 (5.9) | 8 (2.9) | 0.18 |
Chronic obstructive pulmonary disease, n (%) | 0 (0.0) | 9 (3.3) | 0.03 |
Cirrhosis, n (%) | 2 (1.5) | 3 (1.1) | 1.00 |