From: Unexplained chronic liver disease in Ethiopia: a cross-sectional study
Laboratory variable | All patients (n = 150) | Aetiology known (n = 67) | Aetiology unknown (n = 83) |
---|---|---|---|
ALT (U/L) | 34 (22–55) | 41 (24–58) | 30 (21–51)* |
  > URR | 60 (40.0) | 34 (50.7) | 26 (31.3)* |
AST (U/L) | 44 (28–81) | 52 (31–83) | 41 (28–78) |
  > URR | 84 (56.0) | 41 (61.2) | 43 (51.8) |
ALP (U/L) | 317 (207–416) | 315 (250–423) | 320 (200–385) |
  > URR | 80 (53.3) | 37 (55.2) | 43 (51.8) |
GGT (U/L) | 29 (19–48) | 29 (21–47) | 29 (18–52) |
  > URR | 30 (20.0) | 14 (20.9) | 16 (19.3) |
Total bilirubin (μmol/L) | 19 (10–38) | 21 (12–51) | 17 (10–31) |
  > URR | 36 (24.0) | 20 (29.9) | 16 (19.3) |
Albumin (g/L) | 37 (28–50) | 36 (30–50) | 37 (27–50) |
  < LRR | 63 (42.0) | 27 (40.3) | 36 (43.4) |
Creatinine (μmol/L) | 80 (62–97) | 80 (62–97) | 71 (62–88) |
  > URR | 23 (15.3) | 11 (16.4) | 12 (14.5) |
  < LRR | 19 (12.7) | 8 (11.9) | 11 (13.3) |
Platelet count (109/L) | 125 (76–206) | 123 (71–186) | 147 (76–223) |
  < LRR | 75 (50.0) | 36 (53.7) | 39 (47.0) |
IgG (g/L) | 23.9 (17.1–32.5) | 27.0 (16.7–34.2) | 21.6 (17.2–30.6) |
  > URR | 55 (36.7) | 31 (46.3) | 24 (28.9) |
HIV infectiona | 4 (2.7) | 1 (1.5) | 3 (3.6) |
Kato-Katz smear positive | 23 (16.5)b | 13 (21.3)c | 10 (12.8)d |
APRI score > 0.7e | 92 (61.7)f | 46 (69.7)f | 46 (55.4) |
FIB-4 score > 3.25g | 43 (28.9)f | 20 (30.3)f | 23 (27.7) |
APRI score > 0.7 OR FIB-4 score > 3.25 | 94 (63.1)f | 46 (69.7)f | 48 (57.8) |