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Table 2 Risk factors of HBV reactivation in HBsAg-positive patients with hematological malignancy

From: Hepatitis B reactivation among 1962 patients with hematological malignancy in Taiwan

Factors Reactivation
N = 97
No Reactivation
N = 189
Univariate
P value
Multivariate
P Value
Odds ratio(95% CI)
Hematological malignancy    0.332 NA  
 AML 29 46    
  ALL 3 10    
  Lymphoma 46 96    
  CML/MPN 1 5    
  CLL 2 3    
  Myeloma 10 21    
  MDS/AA 6 8    
Age > 65 year    0.052 0.198  
 Yes 11 57    
 No 86 132    
Gender    0.781 NA  
 Man 55 106    
 Woman 42 83    
Hepatitis C    0.180 0.453  
 Yes 4 4    
 No 93 185    
Liver cirrhosis    0.906 NA  
 Yes 4 7    
 No 93 182    
Hepatocellular carcinoma    0.032 <0.001 0.101(0.029–0.355)
 Yes 3 1    
 No 94 188    
Diabetes mellitus    0.388 NA  
 Yes 10 20    
 No 87 169    
Allogeneic transplantation    0.113 0.269  
 Yes 28 31    
 No 69 158    
Antiviral prophylaxis    <0.001 <0.001 4.631(2.902–7.390)
 Yes 26 145    
 No 71 44    
  1. AML acute myeloid leukemia, ALL acute lymphoblastic leukemia, CML/MPN chronic myeloid leukemia/myeloproliferative neoplasm, CLL chronic lymphocytic leukemia, MM myeloma, MDS/AA myelodysplastic syndrome/aplastic anemia