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Table 1 Comparison of median AFP among groups of patient

From: Pre-treatment alphafeto protein in hepatocellular carcinoma with non-viral aetiology – a prospective study

Factor (number within brackets)

AFP level (ng/ml) median and range

P value

Gender (Males 343, 88.2%)

Male 20 (1.16–100,000)

Female 268 (3–26,172)

0.049

Macro vascular invasion (Present 110, 28.3%)

Present 908 (1.16–100,000)

Absent 12.6 (1.48–92,120)

0.002

Tumour diameter (<5 cm 176, 45.2%)

<5 cm 11.5 (1.84–50,000)

>5 cm 32 (1.16–94,120)

0.013

Stage (Early 196, 50.4%)

Early 10.54 (1.48–50,000) (Stage I/II)

Late 202 (1.16–100,000) (Sage III/IV)

0.001

Macroscopic tumour (Nodular 269, 69.1%)

Nodular 9.6 (1.16–50,000)

Diffuse 2308.5 (1.84–100,000)

0.002

Cirrhotic state (Cirrhotics 301, 77.4%)

Cirrhotic 20.4 (1.48–10,000)

Non cirrhotic 65 (1.16–94,120)

0.150

Alcohol consumption (Alcoholics −266, 68.4%)

Alcoholic 26.6 (1.48–94,120)

Non alcoholic 21 (1.16–100,000)

0.197

Diabetes mellitus (Diabetics 234, 60.1%)

Diabetics 26.6 (1.48–100,000)

Non diabetics 22 (1.16–94,120)

0.808

Child-Pugh (Class A - 223, 57.3%)

Class A 12.33(1.66–94,120)

Class B/C 26.03 (1.76–100,000)

0.179

Tumour nodularity (Single 199, 51.2%)

Single 9.6 (1.16–50,000)

Multiple 17.36 (1.85–94,120)

0.119