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Table 2 Event numbers and incidence density (ID) of the outcomes between the study cohorts

From: Add-on neurological benefits of antiviral therapy in HCV patients with chronic kidney disease — a nationwide cohort study

Variable

Treated cohort

(n = 1531)

Untreated cohort

(n = 1531)

P-value‡

All-cause mortality

 Follow-up (years), mean ± SD

3.78 ± 2.66

3.61 ± 2.57

 

 Event number, n (%)

110 (7.18)

237 (15.48)

 

 ID (95% CI)a

19.00 (15.45–22.55)

42.89 (37.43–48.35)

 

 Hazard ratio (95% CI)

0.45 (0.36–0.56)

Reference

<0.001

Acute myocardial infarction

 Follow-up (years), mean ± SD

3.77 ± 2.66

3.59 ± 2.56

 

 Event number, n (%)

12 (0.78)

13 (0.85)

 

 ID (95% CI)a

2.08 (0.90–3.26)

2.36 (1.08–3.65)

 

 Hazard ratio (95% CI)

0.92 (0.42–2.01)

Reference

0.826

Ischemic stroke

 Follow-up (years), mean ± SD

3.75 ± 2.64

3.58 ± 2.56

 

 Event number, n (%)

17 (1.11)

18 (1.18)

 

 ID (95% CI)a

2.96 (1.55–4.37)

3.28 (1.77–4.80)

 

 Hazard ratio (95% CI)

0.91 (0.47–1.76)

Reference

0.774

Hemorrhagic stroke

 Follow-up (years), mean ± SD

3.77 ± 2.66

3.58 ± 2.55

 

 Event number, n (%)

7 (0.46)

23 (1.50)

 

 ID (95% CI)a

1.21 (0.31–2.11)

4.19 (2.48–5.91)

 

 Hazard ratio (95% CI)

0.31 (0.13–0.71)

Reference

0.006

New onset dialysis (n = 2583)b

 Study number

1280

1303

 

 Follow-up (years), mean ± SD

3.93 ± 2.75

3.61 ± 2.61

 

 Event number, n (%)

27 (2.11)

79 (6.06)

 

 ID (95% CI)a

5.37 (3.34–7.39)

16.78 (13.08–20.48)

 

 Hazard ratio (95% CI)

0.31 (0.20–0.48)

Reference

<0.001

  1. SD standard deviation, CI confidence interval
  2. aIncidence density (ID): event numbers per 1000 person-years
  3. bPatients who were under dialysis were excluded
  4. ‡Adjusted for propensity score