Table 2 Genotype distributions of 2 SNPs in ASNS gene
Allele, n (ratio) | Genotype, n (ratio) | Cochran Armitage trend test | logistic regression# | ||||||
|---|---|---|---|---|---|---|---|---|---|
1/2 | 1 | 2 | P/OR (95% CI) | 11 | 12 | 22 | P | P/OR (95% CI) | |
rs1049674 | T/A | ||||||||
HCC (n = 337) | 57(0.085) | 617(0.915) | 0.72 | 2(0.006) | 53(0.157) | 282(0.837) | 0.72 | 0.55 | |
CHB (n = 310) | 49(0.079) | 571(0.921) | 1.08(0.72–1.60) | 3(0.010) | 43(0.139) | 264(0.852) | 1.14(0.75–1.72) | ||
rs34050735 | T/G | ||||||||
HCC (n = 337) | 111(0.165) | 563(0.835) | 0.003 | 13(0.039) | 85(0.252) | 239(0.709) | 0.005 | 0.005 | |
CHB (n = 310) | 67(0.108) | 553(0.892) | 1.63(1.18–2.25) | 6(0.019) | 55(0.177) | 249(0.803) | 1.59(1.15–2.20) | ||