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Fig. 5 | BMC Gastroenterology

Fig. 5

From: Anti-fibrogenic effect of PPAR-γ agonists in human intestinal myofibroblasts

Fig. 5

The mechanism for the anti-fibrogenic effect of PPAR-γ agonists on TGF-β1-induced fibrogenic activation in human primary intestinal myofibroblasts. a The effect of TGF-β1 stimulation on phosphorylation of signaling molecules in HIFs (Western blot). b The effect of Akt inhibitor (LY294002) on TGF-β1 induced expression of Procol1A1, FN, and α-SMA in HIFs (24 h, Western blot). c, d Effect of PPARγ agonists on TGF-β1 induced phosphorylation of Akt and Smad2 in HIFs (24 h, Western blot)

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