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Table 2 Clinical and biochemical characteristics of the children with and without liver steatosis detected with ultrasound

From: Noninvasive assessment of liver steatosis in children: the clinical value of controlled attenuation parameter

Variable

Liver steatosis a

P value

Yes (N = 50)

No (N = 239)

Age, years

11.6 (2.5)

10.8 (3.04)

0.06

Weight, kg

62.2 (16.0)

48.8 (19.7)

<0.001

Height, cm

1.54 (1.4–1.6)

1.47 (1.3–1.6)

.023

BMI, kg/m2

26.8 (4.1)

22.2 (5.5)

<0.001

Waist circumference, cm

86.58 (11.43)

74.1 (17.4)

<0.001

Systolic blood pressure, mmHg

107.65 (11.66)

108.0 (10.1)

0.85

Diastolic blood pressure, mmHg

69.38 (7.12)

68.8 (8.5)

0.67

Total cholesterol, mg/dl

159.1 (29.13)

160.6 (29.8)

0.75

HDL cholesterol, mg/dl

46.9 (10.34)

49.28 (11.0)

0.19

AST, IU/L

24.6 (10.2)

22.18 (8.3)

0.10

ALT, IU/L

32.6 (26.3)

18.16 (13.2)

<0.001

GGT, IU/L

15.2 (6.8)

22.4 (12.3)

<0.001

Fasting blood glucose, mg/dl

76.2 (9.1)

76.8 (10.6)

0.72

Fasting insulin, microIU/ml

15.7 (10.5)

11.8 (8.4)

0.012

HOMA-IR, %

3 (2.2)

2.3 (1.8)

0.04

Triglycerides, mg/dl

86.0 (49.4)

69.1 (30.6)

0.004

Fatty liver index

0.30 (0.20)

0.15 (0.19)

<0.001

Hepatic steatosis index

0.76 (0.24)

0.39 (0.32)

<0.001

CAP, decibel/meter

280.9 (54.1)

217.4 (41.8)

<0.001

LSM, kiloPascal

5.02 (1.03)

4.65 (0.89)

0.01

  1. BMI body mass index; HDL high-density lipoprotein; AST aspartate aminotransferase; ALT alanine aminotransferase; GGT gamma glutamyltransferase; HOMA-IR homeostasis model assessment for insulin resistance; CAP: controlled attenuation parameter; LSM liver stiffness measurement
  2. a Data [mean (SD)] of the 289 children for whom both US and CAP were available