| Univariate analyses | Multivariate analyses | ||
---|---|---|---|---|
Odds ratio (95%CI) | P-value | Odds ratio (95%CI) | P-value | |
Age < 50 years | 1.93 (1.10–3.38) | 0.02 | 1.76 (0.71–4.37) | 0.22 |
Female | 1.26 (0.76–2.09) | 0.37 |  |  |
BMI | 1.02 (0.95–1.10) | 0.51 |  |  |
Alcohol drinking | 0.82 (0.46–1.46) | 0.50 |  |  |
Diabetes Mellitus | 0.78 (0.42–1.45) | 0.44 |  |  |
HCV RNA (log IU/ml) | 0.76 (0.55–1.07) | 0.11 |  |  |
ALT | 0.99 (0.99–1.00) | 0.46 |  |  |
AST | 0.99 (0.99–1.00) | 0.44 |  |  |
Liver fibrosis stage 0–1 | 3.88 (1.83–8.20) | <0.001 | 5.00 (2.02–12.37) | <0.001 |
CYP27B1 rs10877012 CA/AA | 1.67 (0.92–3.02) | 0.09 | 1.24 (0.47–3.29) | 0.67 |
DHCR7 rs12785878 GT/TT | 1.93 (1.05–1.96) | 0.032 | 2.69 (1.03–7.05) | 0.04 |