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Table 2 Characteristics of patients with cirrhosis (N = 11,121)

From: Comparison of risk adjustment methods in patients with liver disease using electronic medical record data

Characteristics

Median (interquartile range) or frequency

Na (mmol/L)

138.4 (135.0–140.0)

Creatinine (umol/L)

66.3 (54.5–81.9)

PT-INR

1.2 (1.0–1.4)

Total bilirubin (umol/L)

27.2 (17.1–59.3)

Albumin (g/dl)

34.7 (29.4–40.0)

CTP scorea

5.0 (5.0–6.0)

MELD score

8.0 (7.0–11.0)

MELDNa score

10.0 (8.0–14.0)

5vMELD score

13.0 (9.0–18.0)

Charlson comorbidity score

1 (0–2)

LOS (day)

13 (5–26)

Age (year)

 18–44

2576 (23.2%)

 45–64

6785 (61.0%)

  ≥ 65

1761 (15.8%)

Male

7773 (69.9%)

Urgent admission

1219 (11.0%)

Na < 135 mmol/L

2764 (24.9%)

Creatinine > 88.4 umol/L

2190 (19.7%)

PT-INR

  < 1.7 (normal range)

10071 (90.6%)

 1.7–2.2

724 (6.5%)

  > 2.2

327 (2.9%)

Total bilirubin (umol/L)

  < 34.2 (normal range)

6564 (59.0%)

 34.2–51.3

1328 (11.9%)

  > 51.3

3230 (29.0%)

Albumin (g/dl)

  > 3.5 (normal range)

5370 (48.3%)

 2.8–3.5

3660 (32.9%)

  < 2.8

2092 (18.8%)

Hepatic encephalopathyb

 Grade I-II

455 (4.1%)

 Grade III-IV (or refractory)

109 (1.0%)

 Severity unknown

1505 (13.5%)

Ascitesb

 Mild

522 (4.7%)

 Moderate to sever

103 (0.9%)

 Severity unknown

5853 (52.6%)

CTP classificationb

 A (CTP score 5–6)

3952 (35.5%)

 B (CTP score 7–9)

1002 (9.0%)

 C (CTP score 10–15)

80 (0.7%)

Number of abnormal CTP variables

 0

2803 (25.2%)

 1

2255 (20.3%)

 2

2390 (21.5%)

  ≥ 3

3674 (33.0%)

Number of Charlson comorbidities

 0

3580 (32.2%)

 1

4564 (41.0%)

 2

2212 (19.9%)

  ≥ 3

766 (6.9%)

Number of Elixhauser comorbidities

 0

2595 (23.3%)

 1

3239 (29.1%)

 2

2355 (21.2%)

  ≥ 3

2933 (26.4%)

Charlson comorbidities

 Myocardial infarction

62 (0.6%)

 Cerebrovascular disease

371 (3.3%)

 Dementia

6 (0.1%)

 Renal disease

1228 (11.0%)

 Any malignancyc

645 (5.8%)

Charlson and Elixhauser shared comorbidities

 Congestive heart failure

25 (0.2%)

 Peripheral vascular disease

7 (0.1%)

 Chronic pulmonary disease

191 (1.7%)

 Rheumatologic disease

62 (0.6%)

 Peptic ulcer disease

1234 (11.1%)

 Diabetes complicated

130 (1.2%)

 Diabetes uncomplicated

3957 (35.6%)

 Hemiplegia or paraplegia

8 (0.1%)

 Metastatic solid tumorc

275 (2.5%)

 AIDS

40 (0.4%)

Elixhauser comorbiditiesd

 Cardiac arrhythmias

447 (4.0%)

 Valvular disease

30 (0.3%)

 Hypertension uncomplicated

2008 (18.1%)

 Hypertension complicated

1156 (10.4%)

 Hypothyroidism

95 (0.9%)

 Lymphoma

20 (0.2%)

 Solid tumor without metastasisc

178 (1.6%)

 Coagulopathy

5 (0.04%)

 Blood loss anemia

335 (3.0%)

 Deficiency anemia

959 (8.6%)

 Depression

41 (0.4%)

 Fluid and electrolyte disorders

1707 (15.4%)

 Alcohol abuse

2780 (25.0%)

 Psychoses

19 (0.2%)

 Renal failure

236 (2.1%)

  1. IQR interquartile range, Na serum sodium, PT-INR international normalized ratio of prothrombin time, LOS length of stay in hospital, CTP Child-Turcotte-Pugh, MELD model for end-stage liver disease, MELDNa MELD sodium, 5vMELD five variable MELD, AIDS acquired immune deficiency syndrome
  2. aCTP score was not available for patients with unknown severity of HE or ascites
  3. bThe sum of proportion of the categories is less than 100% because there were missing values on acsites and hepatic encephalopathy
  4. cExcluded primary liver cancer
  5. dThe obesity, weight loss, pulmonary circulatory disorders, other neurological disorders and drug abuse were excluded due to 0% prevalence