Fig. 5
Western blot and densitometric analysis of apoptotic, autophagic and survival pathways. The images and data reported are obtained from 5 biological replicates. G = Grisù®; V = vitD3; G + V = Grisù® combined with vitD3. Densitometric analysis are expressed as means ± (SD) (%) normalized to control values (defined as 0 %). Caspase 8 p < 0.05: a, d, h, k vs control; e, f, g vs d; g vs k; f, j vs b; a, k vs c; i, j, k vs h; c, i, j vs k; e, j vs a. Beclin p < 0.05: d, f, g, h, j, k vs control; g, k vs c; e, f, g vs d; e, k vs g; f, j vs b; i, j, k vs h; i, j vs k; i vs a. ERK: a, b, c, e, f, g, i. j, k vs control; e vs g; i vs k; a, g, k vs c; e, f, g vs d; i, j, k vs h; f, j vs b; e, i vs a