Table 4 Joint effects of smoking, drinking and MTHFR C677T on pancreatic cancer risk

CC + CT

Never

109

152

1.00

TT

Never

36

50

1.04 (0.62-1.73)

CC + CT

Ever

179

166

1.69 (1.13-2.54)

TT

Ever

36

32

1.94 (1.05-3.57)

P for interaction = 0.79

Drinking

Case patients

Control subjects

OR* (95 % CI)

CC + CT

Never

105

120

1.00

TT

Never

29

27

1.33 (0.72-2.45)

CC + CT

Ever

183

198

1.10 (0.75-1.61)

TT

Ever

43

55

1.05 (0.62-1.78)

P for interaction = 0.38