A meta-analysis of long follow-up outcomes of laparoscopic Nissen (total) versus Toupet (270°) fundoplication for gastro-esophageal reflux disease based on randomized controlled trials in adults

Table 3 Meta-analysis of some outcome parameters after LNF and LTF

Outcome	n		Heterogeneity test		Analysis model	SMD (95 % CI) or RR (95 % CI)	P value
Outcome	LNF	LTF	I ²	P value	Analysis model	SMD (95 % CI) or RR (95 % CI)	P value
Operating time	486	441	77 %	0.0007	Random	SMD –0.54 (–0.84, –0.24)	0.0004
Duration of hospitalization	336	291	13 %	0.28	Fixed	SMD –0.05 (–0.41, 0.32)	0.8
Reoperation	274	282	4 %	0.37	Fixed	RR 3.16 (1.49, 6.68)	0.003
Preoperative DeMeester scores	484	441	0 %	0.45	Fixed	SMD 0.17 (0.02, 0.32)	0.02
Preoperative LES pressure	548	504	20 %	0.29	Fixed	SMD –0.06 (–0.21, 0.09)	0.43
Postoperative esophagitis	317	277	0 %	0.46	Fixed	RR 0.98 (0.81, 1.18)	0.8

LNF laparoscopic Nissen fundoplication, LTF laparoscopic Toupet fundoplication, SMD standard mean difference, RR risk ratio, LES lower esophageal sphincter

ISSN: 1471-230X