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Table 3 Meta-analysis of some outcome parameters after LNF and LTF

From: A meta-analysis of long follow-up outcomes of laparoscopic Nissen (total) versus Toupet (270°) fundoplication for gastro-esophageal reflux disease based on randomized controlled trials in adults

Outcome n Heterogeneity test Analysis model SMD (95 % CI) or RR (95 % CI) P value
LNF LTF I 2 P value
Operating time 486 441 77 % 0.0007 Random SMD –0.54 (–0.84, –0.24) 0.0004
Duration of hospitalization 336 291 13 % 0.28 Fixed SMD –0.05 (–0.41, 0.32) 0.8
Reoperation 274 282 4 % 0.37 Fixed RR 3.16 (1.49, 6.68) 0.003
Preoperative DeMeester scores 484 441 0 % 0.45 Fixed SMD 0.17 (0.02, 0.32) 0.02
Preoperative LES pressure 548 504 20 % 0.29 Fixed SMD –0.06 (–0.21, 0.09) 0.43
Postoperative esophagitis 317 277 0 % 0.46 Fixed RR 0.98 (0.81, 1.18) 0.8
  1. LNF laparoscopic Nissen fundoplication, LTF laparoscopic Toupet fundoplication, SMD standard mean difference, RR risk ratio, LES lower esophageal sphincter