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Table 3 Factors associated with eradication failure in amoxicillin- and tetracycline containing quadruple therapy

From: Comparison of sequential therapy and amoxicillin/tetracycline containing bismuth quadruple therapy for the first-line eradication of Helicobacter pylori: a prospective, multi-center, randomized clinical trial

Factors

Crude

Univariated

Adjusted

Multivariated

OR (95 % CI)

p-valuea

OR (95 % CI)b

p-valuec

Age ≥ 50 (y)

1.12 (0.54–2.32)

0.763

  

Female

0.38 (0.31–1.30)

<0.0001

0.27 (0.34–1.51)

<0.0001

Cigarette smoking

1.35 (0.57–3.20)

0.499

  

Alcohol drinking

1.42 (0.70–2.88)

0.325

  

BMI ≥ 25 (kg/m2)

2.28 (1.12–4.63)

0.023

2.16 (1.05–4.43)

0.037

  1. OR odds ratio, CI confidence intervals, BMI body mass index
  2. aUnivariate logistic regression
  3. bAdjusted for gender and BMI
  4. cMultivariate logistic regression