Skip to main content

Table 2 Clinical, serological and histological characteristics of celiac disease in 1358 patientsa

From: Type 1 and type 2 diabetes in celiac disease: prevalence and effect on clinical and histological presentation

 

DM1

DM2

No diabetes

 

n = 51

n = 38

n = 1269

P value

Females, %

39

61

74

<0.001

Current age, median (range), yr

45 (18–71)

65 (45–83)

52 (20–92)

<0.001

Age at dg of CD, median (range), yr

38 (2–70)

53 (26–76)

42 (2–89)

<0.001

Mode of presentation at dg, %

   

<0.001

Gastrointestinal symptoms

35

50

54

 

Malabsorption

8

24

17

 

Extra-intestinal symptomsb

14

13

16

 

Risk-group screeningc

43

13

14

 

Hb at dg, median (range), g/l

131 (114–152)

134 (112–165)

128 (39–174)

0.272

Anemia at dg, %

20

26

27

0.515

CD in relatives, %

58

61

60

0.964

Positive EmA at dg, %

100

91

88

0.431

Degree of villous atrophy, %

   

0.433

Total

42

36

31

 

Subtotal

29

50

38

 

Partial

29

14

31

 
  1. DM1, type 1 diabetes; DM2, type 2 diabetes
  2. Hb hemoglobin, EmA endomysial antibodies
  3. aCeliac disease patients with or without concomitant DM1 or DM2
  4. bDermatitis herpetiformis, infertility, arthralgia or arthritis, osteoporosis, dental enamel defects, polyneuropathy, hypertransaminasemia, aphtous stomatitis
  5. cDM1, family history for celiac disease, autoimmune thyroid disease, Sjögren’s syndrome