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Table 1 Food intake and body weight data for FVB and Mdr1a –/− mice fed an AIN-76A diet (Control), or fed an AIN-76A diet and orally inoculated with a single dose of a mixture of Enterococcus faecalis and E. faecium cultures and complex intestinal flora (EF.CIF; Inoculation)

From: Inoculation with enterococci does not affect colon inflammation in the multi-drug resistance 1a-deficient mouse model of IBD

Intervention group

Number of micea

Start (End)

Food intakeb (15 weeks of age)

Food intakeb (18 weeks of age)

Body weight (7 weeks of age; start of intervention)c

Body weight (19 weeks of age: after 12 weeks of treatment)c

Fasted body weight before samplingd

(21 or 24 weeks of age)

FVB mice

 

Control

12 (12)

4.5 ± 0.8

4.7 ± 0.5

24.8 ± 1.6

37.1 ± 5.3

34.4 ± 6.0

Inoculation

12 (12)

4.4 ± 0.6

4.7 ± 0.4

24.7 ± 1.1

37.6 ± 2.5

36.0 ± 4.0

Mdr1a –/– mice

 

Controle

12 (8)

4.7 ± 0.2

4.3 ± 1.0

23.6 ± 1.5

30.8 ± 4.3

28.2 ± 4.5

Inoculation

12 (10)

4.8 ± 0.4

4.5 ± 0.5

23.3 ± 1.6

31.4 ± 4.3

28.6 ± 5.0

  1. aEach group had n = 12 mice at the start of the study. In both of the Mdr1a –/– groups some mice either died during the study, or samples were not successfully obtained from these animals, resulting in a reduced number of observations at the end of the study, as shown here. Necropsy was unable to identify a cause of death in any of these cases. These animals were therefore excluded from analyses
  2. bFood intake of all individual mice was measured for two periods of 4 days duration (at age 14-15 and 17-18 weeks). Data are shown as the mean food intake ± SD per group of mice (g per day). Statistically significant differences are described in the results section
  3. cBody weight was measured three times a week. Body weight at the start of the intervention, and after 12 weeks of intervention, is presented here as mean ± SD per group of mice (g). Statistically significant differences are described in the results section
  4. dBody weight was also measured on the day of sampling, after an overnight fast. Mice were either sampled at 21 weeks (sampling group 1) or 24 weeks of age (sampling group 2). For simplicity, combined data from both sampling groups are shown here as the mean ± SD (g). Statistically significant differences are described in the results section
  5. eBecause the inoculation experiment formed part of a larger study (Additional file 1) investigating the effects of dietary polyphenols on colon inflammation [6, 8], data for Mdr1a –/– mice fed the AIN-76A diet (apart from body weight at 19 weeks of age) have already been reported [6]. However, these data are included here for completeness
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BMC Gastroenterology

ISSN: 1471-230X

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