Fig. 3

Assessment of correlations between colon HIS and measures of body weight. To investigate the relationship between colon HIS and body weight, Pearson’s product–moment correlation analyses were performed using R version 3.0.1. There were no significant correlations observed between colon HIS and any measure of body weight using this analysis. Panel a shows the strongest correlation found for the Mdr1a ^–/– Control group, which was that between colon HIS and change in body weight from 7 to 21 weeks of age (R = -0.40, P = 0.07), while panel b shows the strongest correlation found for the Mdr1a ^–/– Inoculation group, which was between colon HIS and fasted body weight prior to sampling (R = -0.40, P = 0.26)