Table 4 The diagnostic properties of “Propionic acid minus Butyric acid (mmol/l)” for the diagnosis of IBS in all subjects and the subgroups of IBS
From: Faecal short-chain fatty acids - a diagnostic biomarker for irritable bowel syndrome?
IBS group | AUC (95 % CI) | Significance | Sens | Spec | Pos. LR | Neg. LR | DOR |
|---|---|---|---|---|---|---|---|
IBS (all subjects) | 0.89 (0.80:0.98) | p < 0.001 | 92 % | 72 % | 3.29 | 0.11 | 29.6 |
IBS-C (no 8) | 0.83 (0.67:0.99) | p = 0.006 | 87.5 % | 72 % | 3.13 | 0.17 | 18.0 |
IBS-D (no 9) | 0.92 (0.78:1.00) | p < 0.001 | 89 % | 72 % | 3.17 | 0.15 | 20.6 |
IBS-M (no 7) | 0.91 (0.81:1.00) | p = 0.001 | 100 % | 72 % | 3.57 | 0.00 | NA |
IBS-U (no 1) | 0.92 (0.81:1.00) | ns (p = 0.16) | 100 % | 72 % | 3.57 | 0.00 | NA |