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Table 1 Clinical background of included studies

From: Surgical outcomes of hepatocellular carcinoma with biliary tumor thrombus: a systematic review

First author (Year) No. M/F Age (years) a BTT type Ma/Mi HBsAg n (%) Anti-HCV n (%) Cirrhosis n (%) TS (cm) a MT n (%) VI n (%) PD n (%) IM n (%) TCA n (%)
Satoh (2000) [5] 17 15/2 58.2 17/0 5 (29.4) 11 (64.8) 5 (29.4)
Shiomi (2001) [6] 17 15/2 58.8 17/0 7 (46.7) 3 (17.6) 6 (35 %) 6.1 12/16 (75) 13 (76) 0 (0) 5 (29)
Peng (2004) [7] 15 b 10/5 49 15/0 13 (86.7) 5.1 2 (13.3) 5 (33.3)
Qin (2004) [8] 34 28/6 48.5 34/0 34 (100) 32 (94.1) 6.4 34 (100)
Yeh (2004) [9] 17 14/3 52.3 17/0 3.8 12/16 (75) 3/11 (27.2) 5/16 (83.3) 2/11 (18.2)
Esaki (2005) [12] 38 32/6 62 19/19 8 (21.1) 10 (26.3) 6.2 19 (50) 27 (71) 11 (28.9) 19 (50)
Ikenaga (2009) [13] 15 12/3 66 10/5 4 (27.7) 7 (46.7) 5.0 6 (40) 12/14 (85.7) 10 (66.7) 2 (13.3)
Luo (2009) [14] 48 c 48/0 6.2
Noda (2011) [15] 22 21/1 58 22/0 15 (68.1) 5 (22.7) 6 (27.2) >5, n = 9 20 (90.9) 13 (59) 18 (81.8)
Shao (2011) [16] 27 24/3 47.1 24/3 26 (96.7) 0 (0) 18 (66.7) >5, n = 10 17 (62.9) 26 (96.3) 5 (18.5) 21 (77.7)
Yu (2011) [17] 20d 17/3 50.6 20/0 16 (80) 14 (70) 4.5 12 (60) 13 (65) 4 (20) 15 (75)
Moon (2013) [18] 73 52/21 54.2 73/0 59 (80.8) 2 (2.8) 62 (84.9) 5.8 11 (15) 53 (72.6) 54 (74) 25 (34.2)
Meng (2014) [19] 35 24/11 51.3 28/7 26 (74.3) 0 (0) 25 (65.8) >5, n = 24 15 (42.8) 10 (25.8) 10 (25.8) 24 (68.6)
Oba (2014) [20] 13 12/1 61 13/0 4 (30.7) 5 (38.5) 3 (23) 4.4 2 (15.4) 12 (92.3)
Kasai (2015) [21] 44 35/9 64 44/0 8 (18.2) 21 (52.5) 14 (31.8) 5.8 16 (36.4) 31 (70.4) 18 (40.9)
Kim (2015) [22] 31 21/10 53 0/31 26 (83.9) 1 (3.2) 4.8 28 (90.3) 1 (3.2) 8 (25.8) 7 (22.5)
Rammohan (2015) [23] 39 28/11 52.1 39/0 7 (17.9) 2 (5.1) Excluded 5.6
Wong (2015) [24] 37 29/8 57 37/0 30 (81.1) 6 15 (29.7) 25 (67.6) 11 (29.7) 35 (94.6)
Yamamoto (2015) [25] 19 19/0 67 19/0 7 (36.8) 4 (21) 6 (31.5) 4.3
Zeng (2015) [26] 37 33/4 50 30/7 29 (78.4) 33 (89.2) 4.9 9 (24.3) 25 (67.5) 23 (62.2) 6 (16.2)
  1. M male, F female, Ma macroscopic, Mi microscopic, HBsAg hepatitis B surface antigen, anti-HCV hepatitis C virus antibody, ST solitary tumor, TS tumor size, MT multiple tumor, VI vascular invasion, PD poor differentiation, IM intrahepatic metastasis, TCA tumor capsule absence
  2. a mean or median
  3. b including 1 patients underwent liver transplantation; c including 5 patients underwent liver transplantation; d including 2 patients underwent liver transplantation