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Table 3 Optimal cut-offs of liver and spleen stiffness for prediction of clinically significant (≥10 mmHg) and severe (≥12 mmHg) portal hypertension

From: Liver and spleen transient elastography predicts portal hypertension in patients with chronic liver disease: a prospective cohort study

HVPG Method Cut-off, kPa Sensitivity, % Specificity, % PPV, % NPV, % Accuracy, %
≥10 mmHg Liver TE 17.4 88.0 87.5 95.8 74.2 88.7
Spleen TE 47.6 77.3 79.2 92.0 52.7 77.7
≥12 mmHg Liver TE 20.6 82.8 80.0 88.8 0.75 83.1
Spleen TE 50.7 78.1 77.1 86.2 65.8 77.7
  1. HVPG hepatic venous pressure gradient, PPV positive predictive value, NPV negative predictive value