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Table 4 Predictors of development of de novo post-transplant type 2 diabetes (adjusted hazard ratio with 95 % confidence interval is calculated using Cox proportional hazard model). Total N used in the model = 13,000: nc = 9999 censored, ne = 3,001 events (de novo DM onset)

From: Risk of de novo post-transplant type 2 diabetes in patients undergoing liver transplant for non-alcoholic steatohepatitis

Predictor aHR (95 % CI) p
NASH 1.29 (1.18–1.41) <.0001
Calendar year 0.92 (0.91–0.94) <.0001
Age at transplant, per year 1.02 (1.01–1.02) <.0001
African-American 1.32 (1.16–1.51) <.0001
Hispanic 1.11 (0.99–1.24) 0.08
Asian 0.99 (0.84–1.17) 0.92
Male gender 1.11 (1.03–1.19) 0.0080
Overweight 1.13 (1.04–1.24) 0.0061
Obese 1.32 (1.21–1.45) <.0001
Liver malignancy 0.96 (0.86–1.08) 0.49
Pre-transplant CAD 1.19 (0.92–1.53) 0.19
Pre-transplant hypertension 1.05 (0.96–1.15) 0.27
Donor’s age, per year 1.002 (1.000–1.004) 0.0414
Procurement from a non-heart-beating donor 1.24 (1.04–1.46) 0.0140
Donor’s history of DM 1.09 (0.96–1.22) 0.18
Use of tacrolimus *) 0.98 (0.83–1.15) 0.80
Use of mycophenolates *) 0.92 (0.84–1.02) 0.11
Use of steroids *) 1.87 (1.49–2.34) <.0001
  1. *) Ever used before the first onset of post-transplant DM
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