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Table 4 Predictors of development of de novo post-transplant type 2 diabetes (adjusted hazard ratio with 95 % confidence interval is calculated using Cox proportional hazard model). Total N used in the model = 13,000: nc = 9999 censored, ne = 3,001 events (de novo DM onset)

From: Risk of de novo post-transplant type 2 diabetes in patients undergoing liver transplant for non-alcoholic steatohepatitis

Predictor

aHR (95 % CI)

p

NASH

1.29 (1.18–1.41)

<.0001

Calendar year

0.92 (0.91–0.94)

<.0001

Age at transplant, per year

1.02 (1.01–1.02)

<.0001

African-American

1.32 (1.16–1.51)

<.0001

Hispanic

1.11 (0.99–1.24)

0.08

Asian

0.99 (0.84–1.17)

0.92

Male gender

1.11 (1.03–1.19)

0.0080

Overweight

1.13 (1.04–1.24)

0.0061

Obese

1.32 (1.21–1.45)

<.0001

Liver malignancy

0.96 (0.86–1.08)

0.49

Pre-transplant CAD

1.19 (0.92–1.53)

0.19

Pre-transplant hypertension

1.05 (0.96–1.15)

0.27

Donor’s age, per year

1.002 (1.000–1.004)

0.0414

Procurement from a non-heart-beating donor

1.24 (1.04–1.46)

0.0140

Donor’s history of DM

1.09 (0.96–1.22)

0.18

Use of tacrolimus *)

0.98 (0.83–1.15)

0.80

Use of mycophenolates *)

0.92 (0.84–1.02)

0.11

Use of steroids *)

1.87 (1.49–2.34)

<.0001

  1. *) Ever used before the first onset of post-transplant DM