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Table 5 Multivariate analysis to investigate the independent factors

From: Comparison of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori eradication in inactive peptic ulcer disease and the efficiency of sequential therapy in inactive peptic ulcer disease and non-ulcer dyspepsia

  Total (N = 408) Eradication failure (N = 70) Eradication success (N = 338) p-value
Age (Mean ± SD) 51.2 ± 11.1 50.7 ± 10.5 51.3 ± 11.1 0.67
Gender (%)     
 Male 144 22 (31.4 %) 122 (36.1 %) 0.46
 Female 264 48 (68.6 %) 216 (63.9 %)  
Adverse event (%)     
 Yes 140 16 (22.9 %) 124 (36.7 %) 0.03
 No 268 54 (77.1 %) 214 (63.3 %)  
There is no statistically difference between eradication rate, gender, and age. The success group have more adverse event.
iDU Total failure in iDU (N = 26) Failure in Triple (N = 10) Failure in Sequential (N = 16) p-value
Age (Mean ± SD) 51.7 ± 9.7 48.5 ± 7.9 53.7 ± 10.4 0.19
Gender (%)     
 Male 9 3 (30.0 %) 6 (37.5 %) 0.7
 Female 17 7 (70.0 %) 10 (62.5 %)  
Adverse event (%)     
 Yes 10 2 (20.0 %) 8 (50.0 %) 0.13
 No 16 8 (80.0 %) 8 (50.0 %)  
In iDU group, there is no statistically difference between failure rate, age, gender, and adverse, event.
Sequential Total failure in Sequential (N = 60) Failure in iDU (N = 16) Failure in NUD (N = 44) p-value
Age (Mean ± SD) 51.0 ± 10.9 53.7 ± 10.4 50.0 ± 11.0 0.26
Gender (%)     
 Male 19 6 (37.5 %) 13 (29.5 %) 0.56
 Female 41 10 (62.5 %) 31 (70.5 %)  
Adverse event (%)     
 Yes 14 8 (50.0 %) 6 (13.6 %) 0.003
 No 46 8 (50.0 %) 38 (86.4 %)  
In sequential group, there is no statistically difference between failure rate, age, and gender. However, the adverse rate is statistically higher in iDU group.