Table 2 Characteristic of selected studies in the meta-analysis
From: Prognostic and clinical significance of syndecan-1 in colorectal cancer: a meta-analysis
Author | Clinical parameters assessment (number) | Scoring system (Positivity cells) | Number of patients | Epitope retrieval method |
|---|---|---|---|---|
Wang et al | T, L, H, D, F. (52) | histoscore = area × intensitya | High level (26), Low level (26) | NA |
Yang et al | F. (58) | histoscore = area × intensitya | Positive (19), Negative (39) | HIER |
Pap et al | T, L, H, D. (117) | Frequency of cells + intensityb | G0 (2), G1-3 (115) | pressurized steam cooking |
Hashimoto et al | T, L, H, D, F. (131) | 0 (< 5 %); 1+ (5 % – 25 %); 2+ (25 % – 75 %), 3+ (> 75 %) | 0 (38), 1+(27), 2+(49), 3+(17) | antigen retrieval solution |
Qi et al | T, L, H, D, E. (52) | 0 (< 5 %); 1+ (5 % – 25 %); 2+ (25 % – 75 %), 3+ (> 75 %) | Positive (34), Negative (18) | HIER |
Feng et al | T, L, H, D, E. (31) | 0 (< 5 %); 1+ (5 % – 25 %); 2+ (25 % – 75 %), 3+ (> 75 %) | Positive (25), Negative (6) | HIER |
Lundin et al | T, H, F. (237) | Weak: < 30 %, Strong: > 30 % | Weak (86), Strong (151) | NA |
Zhou et al | T, L, H. (52) | 0 (< 5 %); 1+ (5 % – 25 %); 2+ (25 % – 75 %), 3+ (> 75 %) | 0 (18), 1+(13), 2+(14), 3+(7) | HIER |
Zuo et al | T, L, H, D, E. (51) | 0 (< 5 %); 1+ (5 % – 50 %); 2+ (> 50 %) | 0 (31), 1+(17), 2+ (3) | HIER |
Fujiya et al | T, L, F. (105) | – (< 5 %); + (5 % – 25 %); ++ (25 % – 75 %), +++ (> 75 %) | – & ± (36), + & ++ (69) | HIER |