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Table 3 Predictors of recurrence after LT for HCC

From: Excessive intraoperative blood loss independently predicts recurrence of hepatocellular carcinoma after liver transplantation

Variable Univariate analysis Multivariate analysis
P HR (95 % CI) P
Age <60 years 0.004 1.43 (1.03–1.99) 0.033
Male sex 0.025 1.07 (0.62–1.86) 0.808
Hepatitis B virus infection 0.604  
Pre-LT tumor therapy 0.126  
MELD score > 15 0.472  
AFP levels > 400 ng/mL <0.001 1.65 (1.24–2.19) 0.001
Poor differentiation 0.030 1.26 (0.84–1.88) 0.263
Macrovascular invasion <0.001 3.19 (2.30–4.12) <0.001
Microvascular invasion <0.001 1.84 (1.38–2.47) <0.001
Beyond Milan criteria <0.001 2.54 (1.79–3.59) <0.001
Blood transfusion 0.496  
IBL > 4 L <0.001 2.32 (1.60–3.36) <0.001
Operation time > 8 h 0.128