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Table 2 Histological analysis results obtained with the EF method (see Methods section) in 11 coeliac patients presenting the same grade before and after gluten withdrawal when analyzed by the classical Marsh-Oberhuber scoring system

From: Histological evaluation of duodenal biopsies from coeliac patients: the need for different grading criteria during follow-up

  Marsh-Oberhuber grade (%)a
At Diagnosis During GFD   
Patient 3a 3b 3c IELs % 0 1 2 3a 3b 3c IELs % Years after diagnosis (n) Outcome
1 0 0 100 31 0 0 0 15 0 85 48 3 I
2 0 0 100 23 0 0 0 50 35 15 45 2 I
3 10 90 0 47 0 0 0 0 95 5 64 13 W
4 0 0 100 49 50 20 0 0 0 30 31 9 I
5 100 0 0 4 20 0 5 75 0 0 12 1 I
6 0 100 0 53 0 0 0 0 100 0 35 7 U
7 0 40 60 27 0 0 0 0 0 100 34 1 W
8 0 0 100 56 0 0 5 0 20 75 61 1 I
9 0 0 100 45 0 0 0 0 40 60 38 6 I
10 0 0 100 55 0 10 0 0 30 60 32 1 I
11 70 30 0 42 0 0 0 20 80 0 46 2 I
  1. a % of area covered, IELs intraepithelial lymphocytes, GFD gluten-free diet, I improved, MO Marsh-Oberhuber, W worsened, U unchanged