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Table 1 Parameters during esophageal body contractions with and without administration of acotiamide

From: Effects of acotiamide on esophageal motor function and gastroesophageal reflux in healthy volunteers

  Supine position p value Sitting position p value
Control Acotiamide Control Acotiamide
Segment 1 (mmHg) 55.4 [46.0–59.7] 64.1 [55.0–70.8] 0.02 52.8 [40.8–54.7] 56.1 [42.8–58.0] 0.18
Segment 2 (mmHg) 81.9 [68.5–96.1] 90.5 [72.8–93.7] 0.33 65.3 [62.8–75.8] 54.3 [49.7–71.9] 0.04
Segment 3 (mmHg) 103.9 [93.7–109.4] 106.7 [84.4–124.5] 0.58 89.9 [77.0–99.7] 88.8 [75.4–93.5] 0.96
LES pressure (mmHg) 19.8 [18.0–25.1] 21.9 [18.4–24.1] 0.88 15.0 [11.4–21.0] 14.3 [8.5–20.9] 0.58
CFV (cm/s) 5.7 [4.6–6.1] 5.5 [4.5–6.5] 0.96 5.0 [4.2–6.5] 4.8 [4.4–5.4] 0.58
  1. LES Lower esophageal sphincter, CFV Contractile front velocity. Values are expressed as median. Number of brackets show interquartile range of each pattern