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Table 2 Comparison of trough serum infliximab (IFX) levels, partial Mayo Score and C-reactive protein (CRP) levels in subgroups of ulcerative colitis patients 2 weeks after the initiation of IFX infusion

From: C-reactive protein level at 2 weeks following initiation of infliximab induction therapy predicts outcomes in patients with ulcerative colitis: a 3 year follow-up study

Variable IFX responders (n = 29) IFX partial-responders (n = 24) IFX non-responders (n = 19) P1 Value P2 Value
Trough IFX (μg/mL) 23.3 [18.9–29.7] 30.9 [17.7–42.7] 25.0 [21.6–31.5] 0.1825 0.4436
Partial Mayo Score (0–9) 1.0 [0–3.0] 5.0 [3.0–6.0] 7.0 [3.0–8.0] <0.0001 <0.0001
CRP (mg/dL) 0.07 [0.02–0.24] 0.19 [0.08–0.67] 0.43 [0.16–2.13] 0.0135 0.0084
CRP (week 2/week 0) ratio 0.06 [0.02–0.21] 0.39 [0.08–0.97] 1.00 [0.29–1.89] 0.0025 <0.0001
  1. Data are presented as the median [interquartile range] values and compared by Wilcoxon-Mann–Whitney test
  2. P1, responder vs partial-responder; P2: responder vs no-responder