Fig. 2

Hepatic lipid accumulation in mice fed custom MCS and MCD diets. a Photomicrographs illustrate liver histology after 21 days of MCS or MCD feeding. There was no apparent steatosis in any of the MCS-fed groups. MCD diets induced histologic steatosis of varying degrees depending upon macronutrient composition. Bar = 100 μm. b Total hepatic triglyceride measured biochemically in MCS and MCD livers at 21 days. Values represent mean ± SE for n = 10. c Total hepatic fatty acid content measured by gas chromatography and d total hepatic fatty acid segregated by SFA, MUFA and PUFA. Values represent mean ± SE for n = 5. St Ol = Starch Oleate, St Palm = Starch Palmitate, Suc Ol = Sucrose Oleate, Suc Palm = Sucrose Palmitate. Superscripts indicate P < 0.05 vs. MCD comparison groups by number