Table 4 Correlation of NAMPT haplotypes with ESCC susceptibility
From: Genetic polymorphisms of NAMPT related with susceptibility to esophageal Squamous cell carcinoma
Haplotype | Cases (n = 405) | Controls (n = 405) | P a | ORa(95% CI) | ||
|---|---|---|---|---|---|---|
n | % | n | % | |||
a = TTC | ||||||
−/−b | 258 | 63.70 | 204 | 50.37 | 1.00 | 1.00 |
-/a + a/a | 147 | 36.30 | 201 | 49.63 | <0.01 | 0.61 (0.46-0.79) |
b = TAC | ||||||
−/− | 237 | 58.52 | 195 | 48.15 | 1.00 | 1.00 |
-/b + b/b | 168 | 41.48 | 210 | 51.85 | <0.01 | 0.69 (0.52-0.90) |
c = CTC | ||||||
−/− | 111 | 27.41 | 147 | 36.30 | 1.00 | 1.00 |
-/c + c/c | 294 | 72.59 | 258 | 63.70 | <0.01 | 1.57 (1.16-2.12) |
d = CTT | ||||||
−/− | 354 | 87.41 | 372 | 91.85 | 1.00 | 1.00 |
-/d + d/d | 51 | 12.59 | 33 | 8.15 | 0.04 | 1.72 (1.03-2.85) |
e = CAC | ||||||
−/− | 336 | 82.96 | 381 | 94.07 | 1.00 | 1.00 |
-/e + e/e | 69 | 17.04 | 24 | 5.93 | <0.01 | 3.39 (1.99-5.75) |