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Table 4 Correlation of NAMPT haplotypes with ESCC susceptibility

From: Genetic polymorphisms of NAMPT related with susceptibility to esophageal Squamous cell carcinoma

Haplotype Cases (n = 405) Controls (n = 405) P a ORa(95% CI)
n % n %
a = TTC       
 −/−b 258 63.70 204 50.37 1.00 1.00
 -/a + a/a 147 36.30 201 49.63 <0.01 0.61 (0.46-0.79)
b = TAC       
 −/− 237 58.52 195 48.15 1.00 1.00
 -/b + b/b 168 41.48 210 51.85 <0.01 0.69 (0.52-0.90)
c = CTC       
 −/− 111 27.41 147 36.30 1.00 1.00
 -/c + c/c 294 72.59 258 63.70 <0.01 1.57 (1.16-2.12)
d = CTT       
 −/− 354 87.41 372 91.85 1.00 1.00
 -/d + d/d 51 12.59 33 8.15 0.04 1.72 (1.03-2.85)
e = CAC       
 −/− 336 82.96 381 94.07 1.00 1.00
 -/e + e/e 69 17.04 24 5.93 <0.01 3.39 (1.99-5.75)
  1. aLogistic regression model, adjusted for age, gender, tobacco smoking and alcohol consumption.
  2. bThe minus sign (−) denotes any haplotype. For example: −/a indicates the a haplotype in combination with any other haplotype.